1st Edition

Structure and Functions of Amine Oxidases

By Bruno Mondovi Copyright 1985

    A good portion of this book has been devoted to the copper-dependent enzymes, these being the more numerous. The chapter dealing with serum amine oxidases also focuses attention on their catalytic mechanism, as these enzymes have been studied in greater depth.As the presentation of topics whose experimental basis is rapidly developing is likely to stimulate the reader‘s interest, many bibliographic references have been included.Readers could find this book poor, as far as many topics are dealt with in a relatively little space, but we believe it essential to trace the background of our present knowledge in the field of amine oxidases, stressing the future outlook of research on these enzymes, for they are becoming more and more important in general and medical biochemistry.

    1. Introduction 2. Copper Amine Oxidases and Amines as Regulators of Cellular Processes 3. Acetylpolyamines as Subtrates of Amine Oxidases 4. Bacterial and Fungal Amine Oxidases 5. Spermidine Dehydrogenase from Serratia marcescans: A heme-Flavin Enzyme 6 Plant Amine Oxidases 7. Animal Intracellular Amine Oxidases 8. Lysyl Oxidase - Characterization and Clinical Importance 9. Localization of Amine Oxidase in Animal Tissues 10. Plasma Amine Oxidase 11. Optical Spectroscopic Properties of Copper-Containing Amine Oxidases 12. Spectroscopic and Chemical Properties of the Amine Oxidase Copper 13. Inhibitors of Copper Amine Oxidases 14. Diamine Oxidase in Developing Tissues 15. Pathophysiological Functions of Diamine Oxidase: An Evaluation in Animal Studies Using a Problematic Model with Several Types of Causal Relationships 16. Diamine Oxidase in Regenerating and Hypertrophic Tissues 17. Diamine Oxidase Activity in Human Tumors: Clinical and Biological Significance 18. Copper-Dependent Amine Oxidases: Clinical Aspects 19. Qualitative Alteration - Transformation - in Catalytic Activity of Amine Oxidases 20. Advances in Monoamine Oxidase Enzymology 21. Inhibitors of FAD-Containing Monoamine Oxidases 22. Physiological and Clinical Aspects of Monoamine Oxidase 23. Human Platelet Monoamine Oxidase 24. Concluding Remarks

    Biography

    Bruno Mondovi