1st Edition

Drug Resistance in Oncology

Edited By S. Bernal Copyright 1997

    This timely new reference integrates the latest clinical results and laboratory studies on the resistance of specific cancers to chemotherapeutic drugs-covering drug resistance in lung, breast, ovary, and colon cancer as well as hematological malignancies.

    Respiratory Cancer

    Chemotherapy Resistance in Small Cell Lung Cancer: Consequences for the Clinician and Future Prospects, Bonne Biesma, Egbert F. Smit, and Pieter E. Postmus
    Multidrug Resistance in Small Cell Lung Cancer, Shelagh E. L. Mirski and Susan P. C. Cole
    Correlations Between Clinical Outcomes and In Vitro Chemosensitivity Testing in Non-Small Cell Lung Cancer (NSCLC), David W. Wilbur
    Liposomal Formulations of Chemotherapeutic Drugs, Samuel D. Bernal, Yuk-Chor Wong, Romulo de Villa, and Gloria Bernas

    Breast Cancer

    Tamoxifen Resistance and Breast Cancer, Lin Soe and Michael W. DeGregorio
    Breast Cancer Resistance to Endocrine Therapy, Per E. Lønning
    Heat Shock Proteins and Drug Resistance in Breast Cancer, Daniel R. Ciocca and Laura M. Vargas Roig

    Other Epithelial Cancers

    Overcoming Drug Resistance in Ovarian Cancer, P. H. B. Willemse, G. J. Veldhuis, A. G. J. van der Zee, and E. G. E. de Vries
    Protein Kinase C Activation and the Intrinsic Drug Resistance of Human Colon Cancer, Catherine A. O'Brian, Karen R. Gravitt, Nancy E. Ward, Krishna P. Guta, Philip J. Bergman, and Constantin G. Ioannides

    Hematological Malignancies

    Clinical Relevance of P-Glycoprotein-Related Multidrug Resistance in Hematological Malignancies, Petra C. Pasman and Harry C. Schouten
    Prediction of Cytotoxic Drug Resistance in Acute Leukemia, Rolf Larsson

    Mechanisms of Drug Resistance

    Determinants of Estramustine Resistance, Lisa A. Speicher and Kenneth D. Tew
    Strategies for Overcoming Anthracycline Resistance, Daniel J. Booser
    Cellular Mechanisms of Cisplatin Resistance, Jeroen Oldeburg and Gerrit Los
    Radiation Response in Chemotherapy-Resistant Tumors, Patrick Miller, Michael Nejad, and David S. Shimm
    Preclinical In Vivo Models of Drug Resistance, Beverly A. Teicher

    Biography

    S. Bernal

    "
    …this book is a very timely update on mechanisms of drug resistance. It is quite comprehensive and is recommended for the clinician engaged in clinical research to whom it will provide an excellent review on the subject.
    "-ASCO OnLine