Considers a new generation of sensors for use in industrial processes, which measure the chemical environment directly by means of a biological agent mainly enzymes so far. Various specialists from Europe, the US, and Japan identify the device's place in their disciplines; review the principles of m
Series Introduction
Preface
Contributors
What is a Biosensor?
Pierre R. Coulet
Amperometric Enzyme Electrodes for Substrate and Enzyme Activity Determinations
Gilbert Bardeletti, Florence Sechaud and Pierre R. Coulet
Development of Amperometric Biosensors for Enzyme Immunoassay
J. V. Bannister, I. John Higgins and Anthony P. F. Turner
Pontentiometric Enzyme Electrodes
Jean-Michel Kauffman and George G. Guilbault
Enzyme Thermistor Devices
Bengt Danielsson
Analytical Applications of Piezoelectric Crystal Biosensors
John H. T. Luong and George G. Guilbault
FET-Based Biosensors
Toshihide Kuriyama and Jun Kimura
Chemically Mediated Fiberoptic Biosensors
Bernhard P. H. Schaffar and Otto S. Wolfbeis
Fluorophore- and Chromophore-Based Fiberoptic Biosensors
Mark A. Arnold
Bioluminescence- and Chemiluminescence- Based Fiberoptic Sensors
Loic J. Blum and Sabine M. Gautier
Immunosensors
Masuo Aizawa
Microbial Biosensors
I. Karube and M. E. SangMok Chang
In Vivo Biosensors
P. Vadgama and M. A. Desai
Trends and Prospects
Loic J. Blum and Pierre R. Coulet
Index
Biography
Loïc J. BLUM is Mâitre de Conférences in Biochemistry and Biotechnology at the Université Claude Bernard de Lyon, France. The author or coauthor of some 30 articles and book chapters, he has concentrated on research in immobilized enzymes on membrane supports, heterogeneous enzymology and the role of mass transfer on enzyme kinetics, bioluminescence and chemiluminescence reactions in the heterogeneous phase, and the development of fiber optic biosensors. Dr. Blum received the doctorat de spécialité (1983) in biochemistry and the doctorat d’état ès sciences (1991) from the Université Claude Bernard de Lyon`., PIERRE R. COULET is Professor of Biochemistry and Biotechnology, and head of the enzyme engineering laboratory at the Université Claude Bernard de Lyon, France. From 1974 to 1983 he served as a researcher at the CNRS (National Center for Scientific Research). The author or coauthor of some 100 articles, reviews, and book chapters, he investigates enzyme engineering and biosensors, including heterogeneous enzymology and membrane-bound enzymes, membrane reactors, and amperometric and optical biosensors. He is an editorial board member of the journals Analytical Letters (Marcel Dekker, Inc.), Analusis, and Analytica Chimica Acta. Professor Coulet received the doctorat de spécialité (1973) in chemistry and biochemistry, and the doctorat d’état ès sciences (1978) from the Université Claude Bernard de Lyon.