Computer Science & Engineering

Computational Biology

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Computational Systems Biology Approaches in Cancer Research

1st Edition

Inna Kuperstein, Emmanuel Barillot
September 16, 2019

Praise for Computational Systems BiologyApproaches in Cancer Research: "Complex concepts are written clearly and with informative illustrations and useful links. The book is enjoyable to read yet provides sufficient depth to serve as a valuable resource for both students and faculty." — Trey Ideker...

Clustering in Bioinformatics and Drug Discovery

1st Edition

John David MacCuish, Norah E. MacCuish
September 05, 2019

With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data. It offers a concise overview of common and recent clustering methods used in bioinformatics and drug discovery....

Metabolomics: Practical Guide to Design and Analysis

1st Edition

Ron Wehrens, Reza Salek
August 21, 2019

Metabolomics is the scientific study of the chemical processes in a living system, environment and nutrition. It is a relatively new omics science, but the potential applications are wide, including medicine, personalized medicine and intervention studies, food and nutrition, plants, agriculture...

An Introduction to Systems Biology: Design Principles of Biological Circuits, Second Edition

2nd Edition

Uri Alon
August 01, 2019

Praise for the first edition: … superb, beautifully written and organized work that takes an engineering approach to systems biology. Alon provides nicely written appendices to explain the basic mathematical and biological concepts clearly and succinctly without interfering with the main text. He...

Microarray Image and Data Analysis: Theory and Practice

1st Edition

Luis Rueda
June 12, 2019

Microarray Image and Data Analysis: Theory and Practice is a compilation of the latest and greatest microarray image and data analysis methods from the multidisciplinary international research community. Delivering a detailed discussion of the biological aspects and applications of microarrays, the...

Omic Association Studies with R and Bioconductor

1st Edition

Juan R. González, Alejandro Cáceres
June 11, 2019

After the great expansion of genome-wide association studies, their scientific methodology and, notably, their data analysis has matured in recent years, and they are a keystone in large epidemiological studies. Newcomers to the field are confronted with a wealth of data, resources and methods....

Computational Biology: A Statistical Mechanics Perspective, Second Edition

2nd Edition

Ralf Blossey
June 04, 2019

Computational biology has developed rapidly during the last two decades following the genomic revolution which culminated in the sequencing of the human genome. More than ever it has developed into a field which embraces computational methods from different branches of the exact sciences: pure and...

Theoretical Physics for Biological Systems

1st Edition

Paola Lecca, Angela Re
January 25, 2019

Quantum physics provides the concepts and their mathematical formalization that lend themselves to describe important properties of biological networks topology, such as vulnerability to external stress and their dynamic response to changing physiological conditions. A theory of networks enhanced...

Modeling the 3D Conformation of Genomes

1st Edition

Guido Tiana, Luca Giorgetti
January 23, 2019

This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand...

Stochastic Modelling for Systems Biology, Third Edition

3rd Edition

Darren J. Wilkinson
November 21, 2018

Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Having been thoroughly updated to reflect this, this third edition covers everything...

Practical Guide to ChIP-seq Data Analysis

1st Edition

Borbala Mifsud, Kathi Zarnack, Anaïs F Bardet
November 05, 2018

Chromatin immunoprecipitation sequencing (ChIP-seq), which maps the genome-wide localization patterns of transcription factors and epigenetic marks, is among the most widely used methods in molecular biology. Practical Guide to ChIP-seq Data Analysis will guide readers through the steps of ChIP-seq...

Systems-Level Modelling of Microbial Communities: Theory and Practice

1st Edition

Aarthi Ravikrishnan, Karthik Raman
September 25, 2018

Systems-Level Modelling of Microbial Communities: Theory and Practice introduces various aspects of modelling microbial communities and presents a detailed overview of the computational methods which have been developed in this area. This book is aimed at researchers in the field of computational/...