Computer Science & Engineering

Computational Biology

Per Page:

Modern Directional Statistics

Christophe Ley, Thomas Verdebout
May 25, 2017

Modern Directional Statistics collects important advances in methodology and theory for directional statistics over the last two decades. It provides a detailed overview and analysis of recent results that can help both researchers and practitioners. Knowledge of multivariate statistics eases the...

Thermostable Proteins: Structural Stability and Design

Srikanta Sen, Lennart Nilsson
May 22, 2017

Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted...

Computational Protein-Protein Interactions

Ruth Nussinov, Gideon Schreiber
May 22, 2017

Often considered the workhorse of the cellular machinery, proteins are responsible for functions ranging from molecular motors to signaling. The broad recognition of their involvement in all cellular processes has led to focused efforts to predict their functions from sequences, and if available,...

Algorithms for Next-Generation Sequencing

Wing-Kin Sung
May 15, 2017

Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for...

X-Machines for Agent-Based Modeling: FLAME Perspectives

Mariam Kiran
May 11, 2017

From the Foreword: "This book exemplifies one of the most successful approaches to modeling and simulating [the] new generation of complex systems. FLAME was designed to make the building of large scale complex systems models straightforward and the simulation code that it generates is highly...

Neuromorphic Photonics

Paul R. Prucnal, Bhavin J. Shastri
May 08, 2017

As society’s appetite for information continues to grow, so does our need to process this information with increasing speed and versatility. Conventional one-size-fits-all solutions offered by digital electronics can no longer satisfy this need, as Moore’s law, interconnection density, and the von...

Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics

Ivan Osorio, Hitten P. Zaveri, Mark G. Frei, Susan Arthurs
March 29, 2017

Epilepsy, one of the most prevalent neurological disorders, affects approximately 1% (greater than 60 million) of the world's population. In an estimated 20 million of these patients, seizures are not controlled even by multiple anti-seizure drugs, and are extremely difficult to predict. Epilepsy:...

Introduction to Integrative Engineering: A Computational Approach to Biomedical Problems

Guigen Zhang
March 01, 2017

This textbook is designed for an introductory course at undergraduate and graduate levels for bioengineering students. It provides a systematic way of examining bioengineering problems in a multidisciplinary computational approach. The book introduces basic concepts of multidiscipline-based...

Statistical Modeling and Machine Learning for Molecular Biology

Alan Moses
January 04, 2017

Molecular biologists are performing increasingly large and complicated experiments, but often have little background in data analysis. The book is devoted to teaching the statistical and computational techniques molecular biologists need to analyze their data. It explains the big-picture concepts...

Bioinformatics Database Systems

Kevin Byron, Katherine G. Herbert, Jason T. L. Wang
December 15, 2016

Modern biological databases comprise not only data, but also sophisticated query facilities and bioinformatics data analysis tools. This book provides an exploration through the world of Bioinformatics Database Systems. The book summarizes the popular and innovative bioinformatics repositories...

Data Analysis for the Life Sciences with R

Rafael A. Irizarry, Michael I. Love
August 10, 2016

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code...

Computational Biology and Bioinformatics: Gene Regulation

Ka-Chun Wong
May 09, 2016

The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the...