Computer Science & Engineering

Computational Biology

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Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R

Gabriel Valiente
June 14, 2017

Emphasizing the search for patterns within and between biological sequences, trees, and graphs, Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis...

Microarray Image Analysis: An Algorithmic Approach

Karl Fraser, Zidong Wang, Xiaohui Liu
June 14, 2017

To harness the high-throughput potential of DNA microarray technology, it is crucial that the analysis stages of the process are decoupled from the requirements of operator assistance. Microarray Image Analysis: An Algorithmic Approach presents an automatic system for microarray image processing to...

Cancer Systems Biology

Edwin Wang
June 14, 2017

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis,...

Biological Sequence Analysis Using the SeqAn C++ Library

Andreas Gogol-Döring, Knut Reinert
June 14, 2017

An Easy-to-Use Research Tool for Algorithm Testing and Development Before the SeqAn project, there was clearly a lack of available implementations in sequence analysis, even for standard tasks. Implementations of needed algorithmic components were either unavailable or hard to access in third-party...

Biological Data Mining

Jake Y. Chen, Stefano Lonardi
June 07, 2017

Like a data-guzzling turbo engine, advanced data mining has been powering post-genome biological studies for two decades. Reflecting this growth, Biological Data Mining presents comprehensive data mining concepts, theories, and applications in current biological and medical research. Each chapter...

Systems Biology and Bioinformatics: A Computational Approach

Kayvan Najarian, Siamak Najarian, Shahriar Gharibzadeh, Christopher N. Eichelberger
May 31, 2017

The availability of molecular imaging and measurement systems enables today’s biologists to swiftly monitor thousands of genes involved in a host of diseases, a critical factor in specialized drug development. Systems Biology and Bioinformatics: A Computational Approach provides students with a...

Neuromorphic Photonics

Paul R. Prucnal, Bhavin J. Shastri
May 30, 2017

As society’s appetite for information continues to grow, so does our need to process this information with increasing speed and versatility. Conventional one-size-fits-all solutions offered by digital electronics can no longer satisfy this need, as Moore’s law, interconnection density, and the von...

Algorithms for Next-Generation Sequencing

Wing-Kin Sung
May 24, 2017

Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for...

Thermostable Proteins: Structural Stability and Design

Srikanta Sen, Lennart Nilsson
May 22, 2017

Thermostable Proteins: Structural Stability and Design provides a comprehensive, updated account of the physical basis of enhanced stability of thermophilic proteins and the design of tailor-made thermostable proteins, paving the way for their possible industrial applications. This book is devoted...

Computational Protein-Protein Interactions

Ruth Nussinov, Gideon Schreiber
May 22, 2017

Often considered the workhorse of the cellular machinery, proteins are responsible for functions ranging from molecular motors to signaling. The broad recognition of their involvement in all cellular processes has led to focused efforts to predict their functions from sequences, and if available,...

Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics

Ivan Osorio, Hitten P. Zaveri, Mark G. Frei, Susan Arthurs
March 29, 2017

Epilepsy, one of the most prevalent neurological disorders, affects approximately 1% (greater than 60 million) of the world's population. In an estimated 20 million of these patients, seizures are not controlled even by multiple anti-seizure drugs, and are extremely difficult to predict. Epilepsy:...

Introduction to Integrative Engineering: A Computational Approach to Biomedical Problems

Guigen Zhang
March 01, 2017

This textbook is designed for an introductory course at undergraduate and graduate levels for bioengineering students. It provides a systematic way of examining bioengineering problems in a multidisciplinary computational approach. The book introduces basic concepts of multidiscipline-based...