Chemistry

Medicinal Chemistry

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C-H Bond Activation in Organic Synthesis

Jie Jack Li
July 01, 2017

Greener than conventional methods, C–H activation methods have flourished during the last decade and become especially attractive to organic chemists. Edited by a practioner in this rapidly developing field, C–H Bond Activation in Organic Synthesis provides an overview of this exciting playground...

Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3

René Roy, Sébastien Vidal
July 01, 2017

Volumes in the Proven Synthetic Methods Series address the concerns many chemists have regarding irreproducibility of synthetic protocols, lack of characterization data for new compounds, and inflated yields reported in chemical communications—trends that have recently become a serious...

Dimethyl Sulfoxide (DMSO) in Trauma and Disease

Stanley W. Jacob, Jack C. de la Torre
July 01, 2017

First isolated as a chemical compound by a Russian chemist in 1866, dimethyl sulfoxide (DMSO) proved to be a near-perfect solvent for decades before its remarkable biological and medical activities were discovered. DMSO is one of the most prodigious agents ever to come out of the world of drug...

Phage Display In Biotechnology and Drug Discovery, Second Edition

Sachdev S. Sidhu, Clarence Ronald Geyer
July 01, 2017

Phage Display in Biotechnology and Drug Discovery, Second Edition provides a comprehensive view of the impact and promise of phage display in drug discovery and biotechnology. Building on the success of its previous edition, the book discusses current theories, principles, and methods in the field...

Drug Repositioning: Approaches and Applications for Neurotherapeutics

Joel Dudley, Laura Berliocchi
June 30, 2017

Nervous system diseases represent a major health concern worldwide. Although important financial and professional investment, their etiology and pathophysiology still remain mostly elusive. Moreover, the clinical need of disease-modifying therapies is still unmet. In the last decades, traditional R...

Applied Biomedical Microbiology: A Biofilms Approach

Daryl S. Paulson
June 30, 2017

From the slippery covering on rocks in a stream, to the clogging slime in a bathtub drain, biofilms are present in everyday life in a variety of forms. This seemingly harmless build-up also accounts for 80 percent of all microbial infections. With chapters authored by experienced contributors from...

Analytical Methods in Combinatorial Chemistry, Second Edition

Bing Yan, Bin Zhang
June 14, 2017

Since the publication of the benchmark first edition of this book, chemical library and combinatorial chemistry methods have developed into mature technologies. There have also been significant shifts in emphasis in combinatorial synthesis. Reflecting the growth in the field and the heightened...

The Inhibitor Index: A Desk Reference on Enzyme Inhibitors, Receptor Antagonists, Drugs, Toxins, Poisons, Biologics, and Therapeutic Leads

Daniel Purich
June 12, 2017

Metabolic inhibitors and receptor antagonists are indispensable tools for the molecular life scientist. By blocking specific enzymes or receptor-mediated signal transduction cascades, they simplify the analysis of complex cellular processes especially when it is essential to demonstrate that a...

Microwave Heating as a Tool for Sustainable Chemistry

Nicholas E. Leadbeater
May 22, 2017

Shorter reaction times, higher product yields, and enhanced selectivity are some of the advantages microwave heating has over conventional methods, causing its use to transition from a curiosity to mainstream, both in industrial and academic settings. Microwave Heating as a Tool for Sustainable...

In Vitro Bioassay Techniques for Anticancer Drug Discovery and Development

Dhanya Sunil, Pooja R Kamath, Raghu Chandrashekhar H
May 01, 2017

This comprehensive and useful handbook represents a definitive up-to-date compendium of key in vitro bioassay methods that are employed to quantify and validate the anticancer activity of a drug candidate before it makes its way in to animal or clinical trials. In Vitro Bioassay Techniques for...

Cancer Inhibitors from Chinese Natural Medicines

Jun-Ping Xu
December 01, 2016

Nature is an attractive source of therapeutic and preventive compounds, and with such chemical diversity found in millions of species of plants, over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines summarizes new...

The Pharmaceutical Index: 2013 Worldwide NCEs

Pharmacodia (Beijing) Co.,Ltd.
November 28, 2016

An ideal drug candidate should possess good pharmacological activity, absorption, distribution, metabolism, excretion and toxicity properties. Historically, there are around 6,000 drugs being used in humans and approximately 3,000 still in clinical use, not including herbal medicines. This...

Conferences

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