Biomedical Science

Pharmacology

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Metallothionein in Biology and Medicine

Curtis D. Klaassen
August 27, 1991

This book brings together work from leading researchers to present the most recent advances in research on metallothionein. This protein interests toxicologists because it is thought that metallothionein protects against metal toxicity and possibly against oxidative stress. It is of interest to...

Calcium Channels: Their Properties, Functions, Regulation, and Clinical Relevance

L. Donald Partridge, John K. Leach
July 03, 1991

The most comprehensive compendium of information available on calcium channelsCalcium channels are a common component of the membranes of a wide range of excitable cells, and their presence is crucial to the functioning of these cells. This book presents a current review of the biophysics,...

Adenosine and Adenine Nucleotides As Regulators of Cellular Function

John W. Phillis
June 14, 1991

This book provides valuable information for investigators interested in the signaling and regulatory functions of adenosine and the adenine nucleotides. Topics covered in this comprehensive volume include the historical development of research on adenosine and adenosine triphosphate; various...

Degradation of Bioactive Substances: Physiology and Pathophysiology

Jens H. Henriksen
May 28, 1991

Intended primarily for researchers working with bioactive substances such as hormones, neurotransmitters, growth factors, and connective tissue makers, this book discusses the principles of degradation in major groups of bioactive materials with respect to physiology, location, and regulation....

Polymers for Controlled Drug Delivery

Peter J. Tarcha
November 21, 1990

Polymers for Controlled Drug Delivery addresses the challenges of designing macromolecules that deliver therapeutic agents that function safely and in concert with living organisms. The book primarily discusses classes of polymers and polymeric vehicles, including particulates, such as latexes,...

Molecular Description of Biological Membrane Components by Computer Aided Conformational Analysis, Volume II

Robert Brasseur
September 25, 1990

The goal of these two volumes is to help fill the gap between theory and experiment in membrane science. This is the only work available today which covers the domain of computer-aided conformational analyses of membranes. Written in a detailed, yet comprehensive manner, this book uses the...

Early Phase Drug Evaluation in Man

O'grady
September 05, 1990

Early Phase Drug Evaluation in Man is a comprehensive, practical guide that covers pre-clinical information relevant to early human studies, including pharmaceutical, metabolic, toxicological, and regulatory aspects, as well as the general considerations relevant to all early human studies. Each...

Transfer RNAs and Other Soluble RNAs

Joseph D. Cherayil
August 29, 1990

This fascinating book discusses various methods that have been used from early times to the present for the isolation and characterization of total tRNA, specific tRNAs, and small molecular weight RNAs. Filled with tables and figures, it presents comparative methods and provides an overview of the...

Methods for Skin Absorption

Barbara W. Kemppainen, William G. Reifenrath
June 13, 1990

This up-to-date volume describes the wide variety of available methods concerning percutaneous absorption of drugs and toxins. It discusses in detail the advantages and disadvantages of each method. This unique publication provides a clear, systematic presentation of each aspect which must be...

Pulsed and Self-Regulated Drug Delivery

Joseph Kost
May 09, 1990

This work focuses on several approaches to modulated control release systems, including polymers responding to external stimuli (pH glucose concentration), polymer drug-magnetic and ultrasonic systems. This book is aimed at the next generation of drug delivery systemsópumps that can be activated to...

Drugs and the Delivery of Oxygen to Tissues

J. Stuart Fleming
December 31, 1989

This rare and unique work consists of a broad overview of hyperviscosity, blood cell deformability, and platelet aggregation. These topics are written in combination with a comprehensive review of drugs bring developed to treat impaired oxygen delivery to tissue. It devotes much attention to the...

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