Biomedical Science

Pharmacology

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Transfer RNAs and Other Soluble RNAs

Joseph D. Cherayil
August 29, 1990

This fascinating book discusses various methods that have been used from early times to the present for the isolation and characterization of total tRNA, specific tRNAs, and small molecular weight RNAs. Filled with tables and figures, it presents comparative methods and provides an overview of the...

Methods for Skin Absorption

Barbara W. Kemppainen, William G. Reifenrath
June 13, 1990

This up-to-date volume describes the wide variety of available methods concerning percutaneous absorption of drugs and toxins. It discusses in detail the advantages and disadvantages of each method. This unique publication provides a clear, systematic presentation of each aspect which must be...

Pulsed and Self-Regulated Drug Delivery

Joseph Kost
May 09, 1990

This work focuses on several approaches to modulated control release systems, including polymers responding to external stimuli (pH glucose concentration), polymer drug-magnetic and ultrasonic systems. This book is aimed at the next generation of drug delivery systemsópumps that can be activated to...

Drugs and the Delivery of Oxygen to Tissues

J. Stuart Fleming
December 31, 1989

This rare and unique work consists of a broad overview of hyperviscosity, blood cell deformability, and platelet aggregation. These topics are written in combination with a comprehensive review of drugs bring developed to treat impaired oxygen delivery to tissue. It devotes much attention to the...

Bioadhesive Drug Delivery Systems

Vincent M. Lenaerts, Robert Gurny
November 30, 1989

This comprehensively written text covers, in-depth, all aspects of bioadhesive systems. Bioadhesive systems are presently playing a major role in the field because of their ability to maintain a dosage form at a precise body-site for a prolonged period of time over which the active principle is...

Topical Drug Delivery Formulations

David W. Osborne, Anton H. Amann
November 27, 1989

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Immunopharmacology

Thomas Rogers
October 15, 1989

Our understanding of the intricate nature of the immune response on both a cellular and molecular level has both contributed to and benefited from the work of immunopharmacologists. An increasing number of immunologists have become interested in agents which exert selective effects on the immune...

Antithrombotic Drugs in Thrombosis Models

Josef Hladovec
August 31, 1989

Antithrombotic Drugs in Thrombosis Models presents a critical review of the use of thrombosis models and an original, highly sensitive methodology for testing antithrombotics based on a more adequate understanding of thrombotic processes. The methods form an integrated system stressing particularly...

Xenobiotic Metabolism and Disposition: The Design of Studies on Novel Compounds

Harry P.A. Illing
February 28, 1989

This publication explains the principles of the techniques used in disposition and metabolism studies in animals, in man, and in vitro. It includes methods for studying routes and rates of absorption, distribution, metabolism, and excretion of novel compounds and their metabolites. Relevant...

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Steven H.Y. Wong
February 01, 1985

This important, new reference provides the first , up-to-date, and comprehensive treatmentof the various liquid chromatography (LC) instrumentation for Therapeutic DrugMonitoring (TDM) and toxicology drug assays and reviews the clinical pharmacologyof major classes of drugs and their LC...

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