Biomedical Science


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Joint Models for Longitudinal and Time-to-Event Data: With Applications in R

Dimitris Rizopoulos
June 22, 2012

In longitudinal studies it is often of interest to investigate how a marker that is repeatedly measured in time is associated with a time to an event of interest, e.g., prostate cancer studies where longitudinal PSA level measurements are collected in conjunction with the time-to-recurrence. Joint...

Physical Activity and Public Health Practice

Barbara E. Ainsworth, Caroline A. Macera
February 22, 2012

Physical activity remains a critical area of research as we consider cost-effective measures for lowering the chronic disease epidemic worldwide. In our increasingly automated society, many adults and children are not active at health-enhancing levels. In Physical Activity and Public Health...

Statistical Thinking in Epidemiology

Yu-Kang Tu, Mark S. Gilthorpe
July 27, 2011

While biomedical researchers may be able to follow instructions in the manuals accompanying the statistical software packages, they do not always have sufficient knowledge to choose the appropriate statistical methods and correctly interpret their results. Statistical Thinking in Epidemiology...

Measurement Error: Models, Methods, and Applications

John P. Buonaccorsi
March 02, 2010

Over the last 20 years, comprehensive strategies for treating measurement error in complex models and accounting for the use of extra data to estimate measurement error parameters have emerged. Focusing on both established and novel approaches, Measurement Error: Models, Methods, and Applications...

Mixed Effects Models for Complex Data

Lang Wu
November 11, 2009

Although standard mixed effects models are useful in a range of studies, other approaches must often be used in correlation with them when studying complex or incomplete data. Mixed Effects Models for Complex Data discusses commonly used mixed effects models and presents appropriate approaches to...

Forensic Epidemiology

Steven A. Koehler, Peggy A. Brown
August 26, 2009

After 9/11, forensic epidemiology emerged as a leading investigative tool, partnering public health officers with law enforcement like never before. Based on the authors’ first-hand experience, Forensic Epidemiology brings to light the vast amounts of information collected by medical examiners that...

Spatial Epidemiological Approaches in Disease Mapping and Analysis

Poh-Chin Lai, Fun-Mun So, Ka-Wing Chan
August 18, 2008

Containing method descriptions and step-by-step procedures, the Spatial Epidemiological Approaches in Disease Mapping and Analysis equips readers with skills to prepare health-related data in the proper format, process these data using relevant functions and software, and display the results as...

Molecular Epidemiology: Applications in Cancer and Other Human Diseases

Timothy R. Rebbeck, Christine B. Ambrosone, Peter G. Shields
May 21, 2008

This volume comprises the investigation of factors that may predict the response to treatment, outcome, and survival by exploring: • design considerations in molecular epidemiology, including: case-only family-based approaches for evaluation of genetic susceptibility to exposure and addiction...

Compendium of Health Statistics: 2008

Emma Hawe, Francois G. Schellevis
January 31, 2008

"The OHE Compendium of Health Statistics" is the one-stop statistical source specially designed for easy use by anyone interested in the UK health care sector and the NHS. It contains over 300 simple, easy-to-read tables and charts and provides a wide range of information on UK health and...

Spatiotemporal Patterns in Ecology and Epidemiology: Theory, Models, and Simulation

Horst Malchow, Sergei V. Petrovskii, Ezio Venturino
December 26, 2007

Although the spatial dimension of ecosystem dynamics is now widely recognized, the specific mechanisms behind species patterning in space are still poorly understood and the corresponding theoretical framework is underdeveloped. Going beyond the classical Turing scenario of pattern formation,...

Geocoding Health Data: The Use of Geographic Codes in Cancer Prevention and Control, Research and Practice

Gerard Rushton, Marc P. Armstrong, Josephine Gittler, Barry R. Greene, Claire E. Pavlik, Michele M. West, Dale L. Zimmerman
November 19, 2007

In the past, disease pattern mapping depended on census tracts based on political units, such as states and counties. However, with the advent of geographic information systems (GIS), researchers can now achieve a new level of precision and flexibility in geographic locating. This emerging...

Basic Concepts in Statistics and Epidemiology

Theodore H. MacDonald, Denis Pereira Gray
December 20, 2006

This book contains a Foreword by Allyson Pollock, Professor and Head, Centre for International Public Health Policy, University of Edinburgh. Healthcare students, practitioners and researchers need a sound basis for making valid statistical inferences from health data. To make the best use of...