Biomedical Science

Biostatistics

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Concise Encyclopedia of Biostatistics for Medical Professionals

Abhaya Indrayan, Martin P. Holt
November 17, 2016

Concise Encyclopedia of Biostatistics for Medical Professionals focuses on conceptual knowledge and practical advice rather than mathematical details, enhancing its usefulness as a reference for medical professionals. The book defines and describes nearly 1000 commonly and not so commonly used...

Patient-Reported Outcomes: Measurement, Implementation and Interpretation

Joseph C. Cappelleri, Kelly H. Zou, Andrew G. Bushmakin, Jose Ma. J. Alvir, Demissie Alemayehu, Tara Symonds
November 16, 2016

Advancing the development, validation, and use of patient-reported outcome (PRO) measures, Patient-Reported Outcomes: Measurement, Implementation and Interpretation helps readers develop and enrich their understanding of PRO methodology, particularly from a quantitative perspective. Designed for...

Clinical Trials in Oncology, Third Edition

Stephanie Green, Jacqueline Benedetti, Angela Smith, John Crowley
October 14, 2016

The third edition of the bestselling Clinical Trials in Oncology provides a concise, nontechnical, and thoroughly up-to-date review of methods and issues related to cancer clinical trials. The authors emphasize the importance of proper study design, analysis, and data management and identify the...

Adaptive Design Theory and Implementation Using SAS and R, Second Edition

Mark Chang
October 14, 2016

Get Up to Speed on Many Types of Adaptive Designs Since the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive trials. Incorporating many of these new developments, Adaptive Design Theory and Implementation Using SAS and R, Second...

Essentials of a Successful Biostatistical Collaboration

Arul Earnest
September 19, 2016

The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in the healthcare field. The book provides valuable insight on where to look for information and material on sample size...

Joint Modeling of Longitudinal and Time-to-Event Data

Robert Elashoff, Gang li, Ning Li
August 24, 2016

Longitudinal studies often incur several problems that challenge standard statistical methods for data analysis. These problems include non-ignorable missing data in longitudinal measurements of one or more response variables, informative observation times of longitudinal data, and survival...

Statistical Methods for Healthcare Performance Monitoring

Alex Bottle, Paul Aylin
August 01, 2016

Healthcare is important to everyone, yet large variations in its quality have been well documented both between and within many countries. With demand and expenditure rising, it’s more crucial than ever to know how well the healthcare system and all its components – from staff member to regional...

Bayesian Designs for Phase I–II Clinical Trials

Ying Yuan, Hoang Q. Nguyen, Peter F. Thall
June 22, 2016

Reliably optimizing a new treatment in humans is a critical first step in clinical evaluation since choosing a suboptimal dose or schedule may lead to failure in later trials. At the same time, if promising preclinical results do not translate into a real treatment advance, it is important to...

Statistical Testing Strategies in the Health Sciences

Albert Vexler, Alan D. Hutson, Xiwei Chen
May 25, 2016

Statistical Testing Strategies in the Health Sciences provides a compendium of statistical approaches for decision making, ranging from graphical methods and classical procedures through computationally intensive bootstrap strategies to advanced empirical likelihood techniques. It bridges the gap...

Benefit-Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments

Qi Jiang, Weili He
May 24, 2016

Guides You on the Development and Implementation of B–R Evaluations Benefit–Risk Assessment Methods in Medical Product Development: Bridging Qualitative and Quantitative Assessments provides general guidance and case studies to aid practitioners in selecting specific benefit–risk (B–R) frameworks...

Multiregional Clinical Trials for Simultaneous Global New Drug Development

Joshua Chen, Hui Quan
April 01, 2016

In a global clinical development strategy, multiregional clinical trials (MRCTs) are vital in the development of innovative medicines. Multiregional Clinical Trials for Simultaneous Global New Drug Development presents a comprehensive overview on the current status of conducting MRCTs in clinical...

Basic Statistics and Epidemiology: A Practical Guide, Fourth Edition

Antony Stewart
February 15, 2016

Basic Statistics and Epidemiology is a straightforward primer in basic statistics that emphasizes its practical use in epidemiology and public health, providing an understanding of essential topics such as study design, data analysis and statistical methods used in the execution of medical research...

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