Biomedical Science


Per Page:

Bayesian Applications in Pharmaceutical Development

1st Edition

Mani Lakshminarayanan, Fanni Natanegara
October 11, 2019

The cost for bringing new medicine from discovery to market has nearly doubled in the last decade and has now reached $2.6 billion. There is an urgent need to make drug development less time-consuming and less costly. Innovative trial designs/ analyses such as the Bayesian approach are essential to...

Clinical Data Quality Checks for CDISC Compliance Using SAS

1st Edition

Sunil Gupta
October 07, 2019

Clinical Data Quality Checks for CDISC Compliance using SAS is the first book focused on identifying and correcting data quality and CDISC compliance issues with real-world innovative SAS programming techniques such as Proc SQL, metadata and macro programming. Learn to master Proc SQL’s subqueries...

Drug Interaction & Lethality Analysis

1st Edition

Marshall N. Brunden, Thomas J. Vidmar, Joseph W. McKean
August 27, 2019

First Published in 1988, Drug Interaction and Lethality Analysis offers a well-structured insight into the relationship between the chemicals we use in everyday life and the environment. With an abundance of references and detailed statistics, this book is highly recommended for students...

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

1st Edition

John O'Quigley, Alexia Iasonos, Björn Bornkamp
August 08, 2019

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of...

Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach

1st Edition

Arkadiy Pitman, Oleksandr Sverdlov, L. Bruce Pearce
July 16, 2019

Mathematical and Statistical Skills in the Biopharmaceutical Industry: A Pragmatic Approach describes a philosophy of efficient problem solving showcased using examples pertinent to the biostatistics function in clinical drug development. It was written to share a quintessence of the authors’...

Bayesian Analysis with R for Drug Development: Concepts, Algorithms, and Case Studies

1st Edition

Harry Yang, Steven Novick
July 11, 2019

Drug development is an iterative process. The recent publications of regulatory guidelines further entail a lifecycle approach. Blending data from disparate sources, the Bayesian approach provides a flexible framework for drug development. Despite its advantages, the uptake of Bayesian...

Textbook of Clinical Trials in Oncology: A Statistical Perspective

1st Edition

Susan Halabi, Stefan Michiels
May 16, 2019

There is an increasing need for educational resources for statisticians and investigators. Reflecting this, the goal of this book is to provide readers with a sound foundation in the statistical design, conduct, and analysis of clinical trials. Furthermore, it is intended as a guide for...

Analysis of Incidence Rates

1st Edition

Peter Cummings
April 15, 2019

Incidence rates are counts divided by person-time; mortality rates are a well-known example. Analysis of Incidence Rates offers a detailed discussion of the practical aspects of analyzing incidence rates. Important pitfalls and areas of controversy are discussed. The text is aimed at graduate...

Clinical Trial Optimization Using R

1st Edition

Alex Dmitrienko, Erik Pulkstenis
March 22, 2019

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as...

Data and Safety Monitoring Committees in Clinical Trials

2nd Edition

Jay Herson
March 22, 2019

Praise for the first edition: "Given the author’s years of experience as a statistician and as a founder of the first DMC in pharmaceutical industry trials, I highly recommend this book—not only for experts because of its cogent and organized presentation, but more importantly for young...

Innovative Strategies, Statistical Solutions and Simulations for Modern Clinical Trials

1st Edition

Mark Chang, John Balser, Jim Roach, Robin Bliss
March 20, 2019

"This is truly an outstanding book. [It] brings together all of the latest research in clinical trials methodology and how it can be applied to drug development…. Chang et al provide applications to industry-supported trials. This will allow statisticians in the industry community to take these...

A Beginner’s Guide to Using Open Access Data

1st Edition

Saif Aldeen Saleh AlRyalat, Shaher Momani
February 11, 2019

Open Access Data is emerging as a source for cutting edge scholarship. This concise book provides guidance from generating a research idea to publishing results. Both young researchers and well-established scholars can use this book to upgrade their skills with respect to emerging data sources,...