Biomedical Science

Biostatistics

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Sample Size Calculations in Clinical Research, Third Edition

Shein-Chung Chow, Jun Shao, Hansheng Wang, Yuliya Lokhnygina
August 30, 2017

Praise for the Second Edition: "… this is a useful, comprehensive compendium of almost every possible sample size formula. The strong organization and carefully defined formulae will aid any researcher designing a study." -Biometrics "This impressive book contains formulae for computing sample size...

Quantitative Methods for HIV/AIDS Research

Cliburn Chan, Michael G. Hudgens, Shein-Chung Chow
August 15, 2017

Quantitative Methods in HIV/AIDS Research provides a comprehensive discussion of modern statistical approaches for the analysis of HIV/AIDS data. The first section focuses on statistical issues in clinical trials and epidemiology that are unique to or particularly challenging in HIV/AIDS research;...

Statistical Optimization of Biological Systems

Tapobrata Panda, Thomas Theodore, R. Arun Kumar
July 26, 2017

A number of books written by statisticians address the mathematical optimization of biological systems, but do not directly address statistical optimization. Statistical Optimization of Biological Systems covers the optimization of bioprocess systems in its entirety, devoting much-needed attention...

Cluster Randomised Trials, Second Edition

Richard J. Hayes, Lawrence H. Moulton
June 27, 2017

Cluster Randomised Trials, Second Edition discusses the design, conduct, and analysis of trials that randomise groups of individuals to different treatments. It explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against...

Clinical Trial Optimization Using R

Alex Dmitrienko, Erik Pulkstenis
June 07, 2017

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as...

Introduction to Data Technologies

Paul Murrell
May 31, 2017

Providing key information on how to work with research data, Introduction to Data Technologies presents ideas and techniques for performing critical, behind-the-scenes tasks that take up so much time and effort yet typically receive little attention in formal education. With a focus on...

Clinical Trial Data Analysis Using R and SAS, Second Edition

Ding-Geng (Din) Chen, Karl E. Peace, Pinggao Zhang
May 03, 2017

Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it …The...

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials

John O'Quigley, Alexia Iasonos, Björn Bornkamp
April 26, 2017

Handbook of Methods for Designing, Monitoring, and Analyzing Dose-Finding Trials gives a thorough presentation of state-of-the-art methods for early phase clinical trials. The methodology of clinical trials has advanced greatly over the last 20 years and, arguably, nowhere greater than that of...

Integrated Microsystems: Electronics, Photonics, and Biotechnology

Krzysztof Iniewski
March 29, 2017

As rapid technological developments occur in electronics, photonics, mechanics, chemistry, and biology, the demand for portable, lightweight integrated microsystems is relentless. These devices are getting exponentially smaller, increasingly used in everything from video games, hearing aids, and...

Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials

Toshiro Tango
February 16, 2017

Repeated Measures Design with Generalized Linear Mixed Models for Randomized Controlled Trials is the first book focused on the application of generalized linear mixed models and its related models in the statistical design and analysis of repeated measures from randomized controlled trials. The...

Biosimilar Clinical Development: Scientific Considerations and New Methodologies

Kerry B. Barker, Sandeep M. Menon, Ralph B. D'Agostino, Sr., Siyan Xu, Bo Jin, PhD
January 17, 2017

Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in...

Bioequivalence and Statistics in Clinical Pharmacology, Second Edition

Scott D. Patterson, Byron Jones
December 20, 2016

Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and...

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