Biomedical Science


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Algorithms for Next-Generation Sequencing

Wing-Kin Sung
May 24, 2017

Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for...

Computational Protein-Protein Interactions

Ruth Nussinov, Gideon Schreiber
May 22, 2017

Often considered the workhorse of the cellular machinery, proteins are responsible for functions ranging from molecular motors to signaling. The broad recognition of their involvement in all cellular processes has led to focused efforts to predict their functions from sequences, and if available,...

Introduction to Integrative Engineering: A Computational Approach to Biomedical Problems

Guigen Zhang
March 01, 2017

This textbook is designed for an introductory course at undergraduate and graduate levels for bioengineering students. It provides a systematic way of examining bioengineering problems in a multidisciplinary computational approach. The book introduces basic concepts of multidiscipline-based...

Statistical Modeling and Machine Learning for Molecular Biology

Alan Moses
January 04, 2017

Molecular biologists are performing increasingly large and complicated experiments, but often have little background in data analysis. The book is devoted to teaching the statistical and computational techniques molecular biologists need to analyze their data. It explains the big-picture concepts...

Data Analysis for the Life Sciences with R

Rafael A. Irizarry, Michael I. Love
August 10, 2016

This book covers several of the statistical concepts and data analytic skills needed to succeed in data-driven life science research. The authors proceed from relatively basic concepts related to computed p-values to advanced topics related to analyzing highthroughput data. They include the R code...

Computational Biology and Bioinformatics: Gene Regulation

Ka-Chun Wong
May 09, 2016

The advances in biotechnology such as the next generation sequencing technologies are occurring at breathtaking speed. Advances and breakthroughs give competitive advantages to those who are prepared. However, the driving force behind the positive competition is not only limited to the...

Big Data: Storage, Sharing, and Security

Fei Hu
May 03, 2016

Although there are already some books published on Big Data, most of them only cover basic concepts and society impacts and ignore the internal implementation details—making them unsuitable to R&D people. To fill such a need, Big Data: Storage, Sharing, and Security examines Big Data management...

Gene-Environment Interaction Analysis: Methods in Bioinformatics and Computational Biology

Sumiko Anno
April 06, 2016

Gene–environment (G × E) interaction analysis is a statistical method for clarifying G × E interactions applicable to a phenotype or a disease that is the result of interactions between genes and the environment. This book is the first to deal with the theme of G × E interaction analysis. It...

Next-Generation Sequencing Data Analysis

Xinkun Wang
February 24, 2016

A Practical Guide to the Highly Dynamic Area of Massively Parallel Sequencing The development of genome and transcriptome sequencing technologies has led to a paradigm shift in life science research and disease diagnosis and prevention. Scientists are now able to see how human diseases and...

The E-Medicine, E-Health, M-Health, Telemedicine, and Telehealth Handbook (Two Volume Set)

Halit Eren, John G. Webster
January 13, 2016

The E-Medicine, E-Health, M-Health, Telemedicine, and Telehealth Handbook provides extensive coverage of modern telecommunication in the medical industry, from sensors on and within the body to electronic medical records and beyond. This two-volume set describes how information and communication...

Big Data Analysis for Bioinformatics and Biomedical Discoveries

Shui Qing Ye
December 22, 2015

Demystifies Biomedical and Biological Big Data Analyses Big Data Analysis for Bioinformatics and Biomedical Discoveries provides a practical guide to the nuts and bolts of Big Data, enabling you to quickly and effectively harness the power of Big Data to make groundbreaking biological discoveries,...

Data Warehousing for Biomedical Informatics

Richard E. Biehl
November 19, 2015

Data Warehousing for Biomedical Informatics is a step-by-step how-to guide for designing and building an enterprise-wide data warehouse across a biomedical or healthcare institution, using a four-iteration lifecycle and standardized design pattern. It enables you to quickly implement a...