Biomedical Science

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Cytochrome P450 2D6: Structure, Function, Regulation and Polymorphism


Shufeng Zhou
March 9, 2016

Cytochromes are proteins that catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singleh...

Biomaterial Mechanics

Heather N. Hayenga, Helim Aranda-Espinoza
May 26, 2017

This book describes the fundamental knowledge of mechanics and its application to biomaterials. An overivew of computer modeling in biomaterials is offered and multiple fields where biomaterials are used are reviewed with particular emphasis to the importance of the mechanical properties of...

Algorithms for Next-Generation Sequencing

Wing-Kin Sung
May 24, 2017

Advances in sequencing technology have allowed scientists to study the human genome in greater depth and on a larger scale than ever before – as many as hundreds of millions of short reads in the course of a few days. But what are the best ways to deal with this flood of data? Algorithms for...

The Handbook of Market Research for Life Science Companies: Finding the Answers You Need to Understand Your Market

Jean-Francois Denault
May 24, 2017

As innovation moves from the lab to the market, a new research phase begins for the entrepreneur: the market research phase. Inspired by a new technology that can change the world, critical questions need to be addressed. Is there a market for my innovation? Who are my clients? What do they need?...

Drug Delivery: An Integrated Clinical and Engineering Approach

Yitzhak Rosen, Pablo Gurman, Noel Elman
May 22, 2017

Integrating the clinical and engineering aspects of drug delivery, this book offers a much needed comprehensive overview and patient-oriented approach for enhanced drug delivery optimization and advancement. Starting with an introduction to the subject and pharmacokinetics, it explores advances for...

Animal Locomotion: Physical Principles and Adaptations

Malcolm S. Gordon, Reinhard Blickhan, John O. Dabiri, John J. Videler
May 22, 2017

Animal Locomotion: Physical Principles and Adaptations is a professional-level, state of the art review and reference summarizing the current understanding of macroscopic metazoan animal movement. The comparative biophysics, biomechanics and bioengineering of swimming, flying and terrestrial...

Clinical Trial Optimization Using R

Rajeshwari V Pandharipande, Erik Pulkstenis
May 16, 2017

Clinical Trial Optimization Using R explores a unified and broadly applicable framework for optimizing decision making and strategy selection in clinical development, through a series of examples and case studies. It provides the clinical researcher with a powerful evaluation paradigm, as well as...

Clinical Trial Data Analysis Using R and SAS, Second Edition

Ding-Geng (Din) Chen, Karl E. Peace, Pinggao Zhang
May 16, 2017

Review of the First Edition "The goal of this book, as stated by the authors, is to fill the knowledge gap that exists between developed statistical methods and the applications of these methods. Overall, this book achieves the goal successfully and does a nice job. I would highly recommend it …The...

Biotechnology in Agriculture and Food Processing: Opportunities and Challenges

Parmjit S. Panesar, Satwinder S. Marwaha
May 16, 2017

An instructive and comprehensive overview of the use of biotechnology in agriculture and food production, Biotechnology in Agriculture and Food Processing: Opportunities and Challenges discusses how biotechnology can improve the quality and productivity of agriculture and food products. It includes...

Targeted Gene Capture for Phylogenetic Systematics and Population Genetics

Chenhong Li, Gavin J. P. Naylor
May 15, 2017

The authors propose a book that reviews Next Generation Sequencing procedures, especially software protocols they created devoted to capturing targeted gene sequences. Such sequences are used by phylogenetists and population geneticists. The book will provide background and recommendations that...

Biomaterials for Cell Delivery: Vehicles in Regenerative Medicine

Aaron S. Goldstein
May 15, 2017

The purpose of this book is to summarize key strategies and recent accomplishments in the area of developing cell/biomaterial constructs for regenerative medicine. The first section is a review of the state-of-the-art of biomaterial carriers and is divided into synthetic and natural materials. A...

Dosimetry in Bioelectromagnetics

Marko Markov
May 11, 2017

Dosimetry refers to the calculation and assessment of the radiation dose received by the human body. The proposed book will place emphasis on the existence of physical and biophysical dosimetry. It will be discussed for the proper description and evaluation of the signal at the power generation...

Handbook of Primate Behavioral Management

Steven J. Schapiro
May 10, 2017

The Handbook of Primate Behavioral Management (HPBM) fills a void in the scientific literature, providing those who work with nonhuman primates (NHPs) with a centralized reference for many issues related to the care and behavioral management of captive nonhuman primates. While there are numerous...