Biomedical Science

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Cytochrome P450 2D6: Structure, Function, Regulation and Polymorphism

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Shufeng Zhou
March 9, 2016

Cytochromes are proteins that catalyze electron transfer reactions of well-known metabolic pathways and are classified in various superfamilies. The CYP, or P450, superfamily accounts for 90% of the oxidative metabolism of clinical drugs. One member of this superfamily, P450 2D6 (or CYP2D6), singleh...

Toxins and Other Harmful Compounds in Foods

A. Witczak, Zdzislaw Sikorski
January 24, 2017

Toxins and Other Harmful Compounds in Foods provides information on the contents, distribution, chemical properties, and biological activity of toxins and other harmful compounds in foods that are natural components of the raw materials, accumulated due to microbial actions and environmental...

Biosimilar Clinical Development: Scientific Considerations and New Methodologies

Kerry B. Barker, Sandeep M. Menon, Ralph B. D'Agostino, Sr., Siyan Xu, Bo Jin, PhD
January 17, 2017

Biosimilars have the potential to change the way we think about, identify, and manage health problems. They are already impacting both clinical research and patient care, and this impact will only grow as our understanding and technologies improve. Written by a team of experienced specialists in...

Articular Cartilage, Second Edition

Kyriacos A. Athanasiou, Eric M. Darling, Jerry C. Hu, Grayson D. DuRaine, A. Hari Reddi
January 17, 2017

This book covers the latest research and advancements related to articular cartilage in biology, development, pathology, clinical applications and tissue engineering. The authors take an interdisciplinary approach that encompasses the breadth and depth of basic science, bioengineering,...

Heat and Mass Transfer: A Biological Context, Second Edition

Ashim K. Datta
January 17, 2017

This substantially revised text represents a broader based biological engineering title. It includes medicine and other applications that are desired in curricula supported by the American Society of Agricultural and Biological Engineers, as well as many bioengineering departments in both U.S. and...

Schizophrenia: A Practical Primer for Clinicians and Allied Health Professionals, Second Edition

Ravinder Reddy, Matcheri S. Keshavan
January 15, 2017

Schizophrenia is a devastating illness that affects well over 20 million people worldwide and is one of the top ten causes of disability in developed countries. Because patients with schizophrenia are encountered in many health care provider settings, a broad range of health practitioners should to...

Chemical Exchange Saturation Transfer Imaging: Advances and Applications

Michael T. McMahon, Assaf A. Gilad, Jeff W.M. Bulte, Peter C.M. van Zijl
January 12, 2017

This is the first textbook dedicated to CEST imaging and covers the fundamental principles of saturation transfer, key features of CEST agents that enable the production of imaging contrast, and practical aspects of preparing image-acquisition and post-processing schemes suited for in vivo...

Hybrid Nanomaterials: Design, Synthesis, and Biomedical Applications

Weibo Cai, Feng Chen
January 11, 2017

Over the last decade, an unprecedented expansion in the field of nanomedicine has resulted in the development of new nanomaterials for diagnosis and therapy of various diseases such as cancer. This book covers the design, synthesis and applications of various functionally-hybridized nanomaterials...

Healthcare Technology Management – A Systematic Approach

Francis Hegarty, John Amoore, Paul Blackett, Justin McCarthy, Richard Scott
January 10, 2017

Healthcare Technology Management: A Systematic Approach offers a comprehensive description of a method for providing safe and cost effective healthcare technology management (HTM). The approach is directed to enhancing the value (benefit in relation to cost) of the medical equipment assets of...

Statistical Modeling and Machine Learning for Molecular Biology

Alan Moses
January 04, 2017

Molecular biologists are performing increasingly large and complicated experiments, but often have little background in data analysis. The book is devoted to teaching the statistical and computational techniques molecular biologists need to analyze their data. It explains the big-picture concepts...

Therapeutic Applications of Adenoviruses

Philip Ng, Nicola Brunetti-Pierri
December 21, 2016

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene...

Bioequivalence and Statistics in Clinical Pharmacology, Second Edition

Scott D. Patterson, Byron Jones
December 20, 2016

Maintaining a practical perspective, Bioequivalence and Statistics in Clinical Pharmacology, Second Edition explores statistics used in day-to-day clinical pharmacology work. The book is a starting point for those involved in such research and covers the methods needed to design, analyze, and...

Advances in Pulmonary Drug Delivery

Philip Chi Lip Kwok, Hak-Kim Chan
December 20, 2016

The respiratory tract has been used to deliver biologically active chemicals into the human body for centuries. However, the lungs are complex in their anatomy and physiology, which poses challenges to drug delivery. Inhaled formulations are generally more sophisticated than those for oral and...

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