Translational Research in Traumatic Brain Injury

Daniel Laskowitz, Gerald Grant

October 9, 2015 by CRC Press
Reference - 412 Pages - 9 Color & 34 B/W Illustrations
ISBN 9781466584914 - CAT# K19065
Series: Frontiers in Neuroscience

USD$149.95

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Features

  • Covers the spectrum of TBI, from mild sports-related injuries to severe blast injuries
  • Discusses fundamental cell mechanisms and pathophysiology, as well as animal modeling, clinical diagnosis, current therapeutic strategies, and future treatments
  • Describes long-term neuropsychiatric symptoms and the relationship of TBI to the development of post-concussive syndrome and post-traumatic stress disorder
  • Features chapters written by international leaders across multiple disciplines, including neurobiology, neurology, neurosurgery, intensive care medicine, psychiatry, and rehabilitative medicine

Summary

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow.

Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas:

  • Epidemiology
  • Pathophysiology
  • Diagnosis
  • Current treatment strategies and sequelae
  • Future therapies

Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.