Topical Nail Products and Ungual Drug Delivery

1st Edition

S Narasimha Murthy, Howard I. Maibach

CRC Press
Published September 26, 2012
Reference - 282 Pages
ISBN 9781439811290 - CAT# K10565

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Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.

A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.

Topics Include

  • Nail anatomy, physiology, diseases, and treatment

  • Permeability of the nail plate

  • Topical nail formulations

  • Approaches to enhance ungual and trans-ungual drug delivery

  • In vitro and in vivo models to evaluate topical nail formulations

  • Nail sampling techniques

  • Bioengineering of the nail

  • Trans-ungual iontophoresis

  • Pharmacokinetics of drugs in the nail apparatus

  • Onychopharmacokinetics: proposed model insight

  • Photodynamic therapy of nail diseases

  • The nail as a surrogate for investigating drug use


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