Topical Nail Products and Ungual Drug Delivery

1st Edition

S Narasimha Murthy, Howard I. Maibach

CRC Press
Published September 26, 2012
Reference - 282 Pages
ISBN 9781439811290 - CAT# K10565

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Summary

Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.





A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.





Topics Include







  • Nail anatomy, physiology, diseases, and treatment


  • Permeability of the nail plate


  • Topical nail formulations


  • Approaches to enhance ungual and trans-ungual drug delivery


  • In vitro and in vivo models to evaluate topical nail formulations


  • Nail sampling techniques


  • Bioengineering of the nail


  • Trans-ungual iontophoresis


  • Pharmacokinetics of drugs in the nail apparatus


  • Onychopharmacokinetics: proposed model insight


  • Photodynamic therapy of nail diseases


  • The nail as a surrogate for investigating drug use

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