Therapeutic Applications of Adenoviruses

1st Edition

Philip Ng, Nicola Brunetti-Pierri

CRC Press
Published December 21, 2016
Reference - 256 Pages - 15 Color & 9 B/W Illustrations
ISBN 9781498745482 - CAT# K26945
Series: Gene and Cell Therapy

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Summary

Adenoviruses are double stranded DNA viruses that have been used to study the process of DNA replication. Studies of the mode of action of adenovirally produced tumors in rodents led to the discovery of tumour supressor genes. The adenoviral vector is now the most used vector in clinical gene therapy especially for some kinds of cancers. The chapters in this book focus on the most up-to-date developments in the therapeutic applications of adenoviruses. The intended audience is individuals in the Life Sciences interested in therapeutic applications of adenoviruses. This book reviews the life history and immune responses to adenoviruses and summarizes various therapies implemented with the use of adenoviruses.

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