1st Edition

The Spinal Cord from Gestational Week 4 to the 4th Postnatal Month

By Shirley A. Bayer, Joseph Altman Copyright 2002
    304 Pages 43 Color & 265 B/W Illustrations
    by CRC Press

    This first volume in the Atlas of Human Central Nervous System Development series sets the stage with complete coverage of the spinal cord from gestational week 4 to the 4th postnatal month. 3D color images provide a holistic view of the structural changes during spinal cord morphogenesis. This landmark first volume:

  • Provides quantitative summaries of several ontogenetic trends
  • Features all the stages of spinal cord development
  • Offers fresh insights into the steps involved in the morphogenesis of the mature spinal cord
  • Shows the human spinal cord at its most primitive stage, when consisting mainly of neuroepithelial stem cells
  • This atlas is also available as part of the complete five volume series.

    Preface

    INTRODUCTION
    Overview of Atlas Organization
    Specimen Collections
    Methods: Plate Preparation
    Methods: 3D Reconstructions
    Terminology
    References

    THE FIRST TRIMESTER
    Cervical Levels Only: Embryos at GW4.0 to 8.5
    Spinal Cord of a GW8.5 Embryo
    Spinal Cord of a GW10.5 Embryo

    THE SECOND TRIMESTER
    Spinal Cord of a GW14 Fetus
    Spinal Cord of a GW19 Fetus
    Matched Myelin and Cell Body Stained Sections in the Spinal Cord of a GW26 Fetus

    THE THIRD TRIMESTER
    Matched Myelin and Cell Body Stained Sections in the Spinal Cord of a GW31 Fetus
    Matched Myelin and Cell Body Stained Sections in the Spinal Cord of a GW37 Fetus

    THE EARLY POSTNATAL PERIOD: Infants 4 days, 4 weeks, and 4 months
    Matched Myelin and Cell Body Stained Sections in the Spinal Cord of a 4-day Infant
    Matched Myelin and cell Body Stained Sections in the Spinal Cord of a 4-week Infant
    Matched Myelin and Cell Body Stained Sections in the Spinal Cord of a 4-month Infant

    3D RECONSTRUCTIONS
    The Cervical Level of Eight First-Trimester Specimens
    The Progressive Segregation of Ventral Horn Motoneurons into Columns

    SUMMARY AND CONCLUSIONS
    Changes in Area during the First Trimester
    Developmental Events in Neuronal Populations during the First Trimester
    Changes in Area from GW14 to the 4th Postnatal Month
    Proportional Areas at Cervical Enlargement
    Level Differences in Proportional Areas: GW 8.5-GW19
    Level Differences in Proportional Areas: GW37-4th Month
    Myelination Sequences in Major Fiber Tracts

    GLOSSARY

    Biography

    Shirley A. Bayer, Joseph Altman

    First Prize Winner in the Medicine Category, 2003 British Medical Association Library Book Competition. Also nominated for Best Medical book of 2003
    "First rate."
    -Sidney A. Simon, Ph.D.
    Department of Neurobiology
    Duke University Medical Center

    "The Atlas is very well organized ... Bayer and Altman are outstanding when it comes to thoroughness, competence and aesthetic feeling."
    -Tomas Hökfelt, Ph.D.
    Department of Neuroscience
    Karolinska Institutet, Stockholm, Sweden