1st Edition

The Nanobiotechnology Handbook

Edited By Yubing Xie Copyright 2013
    692 Pages 173 B/W Illustrations
    by CRC Press

    692 Pages 173 B/W Illustrations
    by CRC Press

    A thorough overview of nanobiotechnology and its place in advances in applied science and engineering, The Nanobiotechnology Handbook combines contributions from physics, bioorganic and bioinorganic chemistry, molecular and cellular biology, materials science, and medicine as well as from mechanical, electrical, chemical, and biomedical engineering to address the full scope of current and future developments. World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular and biomedical nanotechnology, biosensors, biocatalysis and biofuel, and education and workforce development. It includes downloadable resources that contain all figures in the book.

    The book begins with discussions of biomimetic nanotechnology, including a comprehensive overview of DNA nanostructure and DNA-inspired nanotechnology, aptamer-functionalized nanomaterials as artificial antibodies, artificial enzymes, molecular motors, and RNA structures and RNA-inspired nanotechnology. It shows how nanotechnology can be inspired by nature as well as adverse biological events in diagnostic and therapeutic development. From there, the chapters cover major important and widely used nanofabrication techniques, applications of nanotechnology for bioprocessing followed by coverage of the applications of atomic force microscopy (AFM), optical tweezers and nanofluidics as well as other nanotechnology-enabled biomolecular and cellular manipulation and detection.

    Focusing on major research trends, the book highlights the importance of nanobiotechnology to a range of medical applications such as stem cell technology and tissue engineering, drug development and delivery, imaging, diagnostics, and therapeutics. And with coverage of topics such as nanotoxicity, responsible nanotechnology, and educational and workforce development, it provides a unique overview and perspective of nanobiotechnology impacts from a researcher’s, entrepreneur’s, economist’s and educator’s point of view. It provides a resource for current applications and future development of nanobiotechnology.

    Part I Biomimetic Nanotechnology

    DNA Nanostructures
    Marya Lieberman

    Aptamer-Functionalized Nanomaterials for Cell Recognition
    Jing Zhou and Yong Wang

    Artificial Enzymes
    James A. Stapleton, Agustina Rodriguez-Granillo, and Vikas Nanda

    Molecular Motors
    Timothy D. Riehlman, Zachary T. Olmsted, and Janet L. Paluh

    From RNA Structures to RNA Nanomachines
    Sabarinath Jayaseelan, Paul D. Kutscha, Francis Doyle, and Scott A. Tenenbaum

    DNA Damage Response Research, Inherent and Future Nano-Based Interfaces for Personalized Medicine
    Madhu Dyavaiah, Lauren Endres, Yiching Hsieh, William Towns, and Thomas J. Begley

    Virus-Based Nanobiotechnology
    Magnus Bergkvist and Brian A. Cohen

    Biomimetic Nanotopography Strategies for Extracellular Matrix Construction
    Esther Lee and Kam W. Leong

    Butterfly Wing–Inspired Nanotechnology
    Rajan Kumar, Sheila Smith, James McNeilan, Michael Keeton, Joseph Sanders,

    Alexander Talamo, Christopher Bowman, and Yubing Xie

    Receptor-Based Biosensors: Focus on Olfactory Receptors and Cell-Free Sensors
    Nadine Hempel

    Part II Nanobiofabrication


    Microcontact Printing
    Jingjiao Guan

    Electron Beam Lithography for Biological Applications
    John G. Hartley

    Laser Direct-Write
    Timothy Krentz, Theresa Phamduy, Brian Riggs, Brian Ozsdolay, and Douglas B. Chrisey

    Electrospinning of Nanofibers
    Andrea M. Unser and Yubing Xie

    Part III Nanobioprocessing

    Applications of Nanotechnology to Bioprocessing
    Susan T. Sharfstein and Sarah Nicoletti

    Part IV Biomolecular and Cellular Manipulation and Detection

    Atomic Force Microscopy
    Gunjan Agarwal and Tanya M. Nocera

    Dielectrophoresis
    Shiqing Wu and Shengnian Wang

    Nanofluidics
    Xin Hu and Weixiong Wang

    Optical Tweezers
    Yingbo Zu, Fangfang Ren, and Shengnian Wang

    Cellular Response to Nanoscale Features
    Manus J.P. Biggs, Matthew J. Dalby, and Shalom J. Wind

    Micro- and Nanotechnologies in Integrative Biology
    Xulang Zhang

    Part V Biomedical Nanotechnology

    Micro- and Nanotechnology in Tissue Engineering
    Jane Wang, Robert Langer, and Jeffrey T. Borenstein

    Nanotechnology in Drug Delivery
    Jungmin Cho, Sungwon Kim, and Kinam Park

    Lipid-Based Nanoparticles for siRNA Delivery
    Bo Yu, L. James Lee, and Robert J. Lee

    Nanodiamonds for Bioimaging and Therapeutic Applications
    V. Vaijayanthimala, Yuen Yung Hui, and Huan-Cheng Chang

    Biomedical Micro-Probe for Super Resolved Image Extraction
    Asaf Shahmoon, Shiran Aharon, Dror Fixler, Hamutal Slovin, and Zeev Zalevsky

    Part VI Nanobiotechnology Impacts

    Nanotoxicity
    Rui Chen and Chunying Chen

    Responsible Nanotechnology: Controlling Exposure and Environmental Release via Rational Design
    Nathaniel C. Cady and Aaron D. Strickland

    Educational and Workforce Development in Nanobiotechnology
    Laura I. Schultz and Daniel D. White

    Index

    Biography

    Yubing Xie

    "…World-class experts discuss the role of nanobiotechnology in bioanalysis, biomolecular and
    biomedical nanotechnology, biosensors, biocatalysis and biofuel, and education and
    workforce development. …The Nanobiotechnology Handbook highlights the
    importance of nanobiotechnology to a range of medical applications such as stem cell
    technology and tissue engineering, drug development and delivery, imaging, diagnostics,
    and therapeutics. And with coverage of topics such as nanotoxicity, responsible
    nanotechnology, and educational and workforce development, it provides an overview
    and perspective of nanobiotechnology impacts from a variety of professional points of
    view."
    ––SirReadaLot.org