The Logic of Biochemical Sequencing examines how to determine the primary structures of proteins and DNA and use them to stimulate the process of logical problem-solving. It concentrates on sequencing work and stresses the thought processes needed to make sense of what might otherwise be indecipherable data. The book also introduces "biocryptography," which serves as a basis for four short stories that use the results of sequence determinations to provide clues to higher order problems. Problems in the book range from elementary to difficult, and solutions to all problems are provided, many of them completely worked out. The book is an excellent supplementary text for students in a full-year biochemistry course, as well as for biochemists and molecular biologists.
Table of Contents
1. End Group Analysis of Proteins 2. Limited Hydrolysis of Proteins 3. Base Sequencing of DNA 4. Analysis of DNA by Restriction Mapping 5. Additional Problems 6. Adventures in Sequencing