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Many developments in immunology have occurred over the past 10 years that give us a better understanding of the immune system and its dysfunctions. Refined mapping of the major histocompatibility complex MHC; elucidation of its gene structure and polymorphism, as well as the molecular basis of MHC restriction; the arrangement, expression, and regulation of immunoglobulins; definition of the structure of the T cell receptor and organization of its genes; and the characterization of soluble factors involved in cell/cell interactions and cloning of their genes are among the major accomplishments. Volumes I and II build on these developments in basic immunology to introduce animal models of various diseases, corresponding human studies, and the genetic analysis of autoimmune traits at the patient population level. The book will be a tremendous asset to immunologists, geneticists, and physicians in various areas of clinical subspecialties.
Table of Contents
Volume II: Immunoglobulin and T Cell Redeptor Genes in SLE Immunogenetics of Systemic Lupus Erythematosus The Genetics of Systemic Lupus Erythematosus The Immunogenetic Basis of Sjogren's Syndrome Immunogenetics of Scleroderma and Mixed Connective Tissue Disease Immunogenetics of Experimental Myasthenia Gravis: Contribution of IgVh Genes Encoding Anti-Dextran Antibodies to Immune Responsiveness Against the Acetylcholine Receptor Immunogenetics of Type II Collagen-Induced Arthritis in Mice Immunogenetics of Rheumatoid Arthritis and Ankylosing Spondylitis Thyroid Autoimmunity in Experimental Models Autoimmune Thyroid Disease Immunogenetics of Type I Diabetes Autoimmune Hepatitis and Other Diseases of the Liver: Immunogenetic Aspects Immunogenetics of Pernicious Anemia Immunogenetic Aspects of Inflammatory Bowel Disease Immunogenetics of Multiple Sclerosis Immuinogenetics of Autoimmune Renal Disease Immunogenetics of Autoimmune Cutaneous Disease Immunogenetics of Autoimmune Polyglandular Syndrome Immunogenetics of AIDS Index
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CHOICE – Outstanding Academic Title – Award Winner
CHOICE – 2018 Outstanding Academic Title – Award Winner
Shingo Research and Professional Publication Award Winner
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