Textbook of Drug Design and Discovery, Third Edition

Tommy Liljefors, Povl Krogsgaard-Larsen, Ulf Madsen

July 25, 2002 by CRC Press
Textbook - 592 Pages
ISBN 9780415282888 - CAT# TF1488

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  • Includes contributions from many of the world's leading experts in medicinal chemistry and pharmaceutical research
  • Contains detailed, color illustrations of molecular models
  • Serves as a comprehensive textbook for students from undergraduate to masters level and beyond
  • Summary

    Building on the success of the previous editions, Textbook of Drug Design and Discovery has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine.

    The book follows drug design from the initial lead identification through optimization and structure-activity relationship with reference to the final processes of clinical evaluation and registration. Chapters investigate the design of enzyme inhibitors and drugs for particular cellular targets such as ion channels and receptors, and also explore specific classes of drug such as peptidomimetics, antivirals and anticancer agents. The use of gene technology in pharmaceutical research, computer modeling techniques, and combinatorial approaches are also included.