Textbook of Drug Design and Discovery

Kristian Stromgaard, Povl Krogsgaard-Larsen, Ulf Madsen

© 2016 - CRC Press
Published August 9, 2016
Textbook - 436 Pages - 327 Color Illustrations
ISBN 9781498702782 - CAT# K24629

For Instructors Request Inspection Copy

was $105.00

USD$84.00

SAVE ~$21.00

Add to Wish List
FREE Standard Shipping!

Features

    • Provides a comprehensive source of information on all facets of modern drug design and discovery
    • Covers basic methods and principles as well as applied and industrial medicinal chemistry
    • Contains contributions from some of the world's leading experts in medicinal chemistry and pharmaceutical research
    • Includes chapters describing the particular challenges and aspects of developing peptide-based drugs as well as a broader description of protein-based drugs
    • Adds a chapter devoted to medicinal chemistry considerations in the pharmaceutical industry when developing hit compounds into lead compounds and later clinical candidates

    Summary

    Building on the success of the previous editions, the Textbook of Drug Design and Discovery, Fifth Edition, has been thoroughly revised and updated to provide a complete source of information on all facets of drug design and discovery for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine. The information is presented in an up-to-date review form with an underlying and fundamental focus on the educational aspects.

    Beginning with an introduction to drug design and discovery, the first eight chapters cover molecular recognition, ligand-based drug design, and biostructure-based drug design. The authors also discuss drug-like properties and decision making in medicinal chemistry, chemical biology, natural products in drug discovery, and in vivo imaging in drug discovery.

    The middle six chapters provide an overview of peptide and protein drug design, prodrugs in drug design and development, and enzyme inhibitors. The authors also go through receptors (structure, function, and pharmacology), ion channels (structure and function), and neurotransmitter transporters (structure, function, and drug binding).

    The following chapters address important neurotransmitter systems, GABA and glutamic acid receptors and transporter ligands, acetylcholine, histamine, dopamine and serotonin, and opioid and cannabinoid receptors. The book concludes with an examination of neglected diseases, anticancer agents, tyrosine kinase receptors, and antibiotics.

    Instructors

    We provide complimentary e-inspection copies of primary textbooks to instructors considering our books for course adoption.

    Request an
    e-inspection copy

    Share this Title