Experts from The Jackson Laboratory and around the world provide practical advice on everything from how to establish a colony to where to go for specific mutations. Systematic Approach to Evaluation of Mouse Mutations includes information on medical photography, grafting procedures, how to map the genes and evaluate the special biological characteristics of the mice.
Table of Contents
Mouse Colony Establishment-Dawnalyn Boggess and John P. Sundberg
Determining the Genetic Basis of a New Trait-Xavier Montagutelli
Computerized Colony Record Keeping-David Larkin
Medical Record Keeping for Project Analysis-Beth A. Sundberg and John P. Sundberg
Necropsy Methods for Laboratory Mice. Biological Characterization of a New Mutation-Melissa J. Relyea, James Miller, Dawnalyn Boggess, and John P. Sundberg
Photography of Mutant Laboratory Mice-John P. Sundberg and James Miller
Comparative Pathology and Animal Model Development-John P. Sundberg and Lloyd E. King, Jr.
Kinetics and Morphometrics-Richard S. Smith, Greg Martin and Dawnalyn Boggess
Ultrastructural Evaluation of Mouse Mutations-Leslie Bechtold
Immunohistochemical and Immunofluoresence Methods-Melissa J. Relyea, John P. Sundberg, and Jerry M. Ward
Radiolabeled cRNA and In Situ Hybridization-Diane S. Keeney
In Situ Hybridization with Non-Radiolabeled Probes-Brian J. Limberg and Charles C. Bascom
Repositories of Mouse Mutations and Inbred, Congenic and Recombitant Inbred Strains-Muriel T. Davisson and John Sharp
"The Jackson Lab crew, with assists from other contributors, have put together a reference for scientists, mouse geneticists, managers and lab animal veterinarians. … This new edition is a valuable reference for those involved with transgenic mice and mice colonies where specific mutations are maintained as research models."
-Mark Klinger in Laboratory Animal Practitioner