Sumoylation: Molecular Biology and Biochemistry

1st Edition

Van G. Wilson

Taylor & Francis
Published May 13, 2004
Reference - 350 Pages - 45 B/W Illustrations
ISBN 9780954523282 - CAT# RU37136

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Summary

The molecular and biochemical mechanisms involved in sumoylation have been the subject of intense interest in recent years. This volume, edited and written by leading international experts, is the first book to be devoted to sumoylation. It presents information on the history, evolution and mechanisms of sumoylation, discusses SUMO proteases, ligases and conjugation pathways, and reviews the impact on modification and nucleocytoplasmic transport, PML nuclear bodies, and transcriptional regulation. In addition, specialist chapters cover the role of sumoylation in yeast, viruses and the tumor suppressor P53.

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