1st Edition

Stress Proteins in Medicine

Edited By Willem Van Eden, Douglas B. Young Copyright 1995

    Provides a thorough overview of current knowledge of stress proteins in both normal and disease physiology and evaluates the potential for developing novel diagnostic, prophylactic, and therapeutic approaches to control human disease based on the latest stress-protein research.

    Overview

    Stress Proteins as Molecular Chaperones
    The Unique Role of Heat Shock Proteins in Infections
    Clinical Implications of the Stress Response
    T-Lymphocyte Recognition of Hsp 60 in Experimental Arthritis
    Heat Shock Protein 60 and the Regulation of Autoimmunity

    Stress Proteins and Specific Immune Responses

    Immune Responses to Heat Shock Proteins in Reactive Arthritis
    Juvenile Chronic Arthritis and Heat Shock Proteins
    T-Cell Responses to Heat Shock Proteins in Rheumatoid Arthritis
    Heat Shock Protein 60 Autoimmunity in Lyme Disease
    Stress Proteins in Behçet's Disease and Experimental Uveitis
    Stress Proteins in Systemic Lupus Erythematosus
    Expression of and Immune Response to Heat Shock Protein 65 in Crohn's Disease
    Stress Proteins in Multiple Sclerosis and Other Central Nervous System Diseases
    Heat Shock Protein 60 and Insulin-Dependent Diabetes Mellitus
    Protection Against Tumors by Stress Protein Gene Transfer
    Immune Responses to Stress Proteins in Mycobacterial Infections
    Heat Shock Proteins in Fungal Infections
    Stress Proteins and Infertility
    Heat Shock Proteins in Visceral Leishmaniasis
    Role of Heat Shock Protein Immunity in Transplantation

    Stress Proteins and Expression in Diseased Tissue

    Lupus and Heat Shock Proteins
    Sarcoidosis
    Stress Proteins in Inflammatory Liver Disease
    Helicobacter pylori-Associated Chronic Gastritis
    Jejunal Epithelial Cell Stress Protein Expression in Gluten-Induced Enteropathy (Celiac Disease)
    Identification of Endogenous Heat Shock Protein 60 as an Autoantigen in Autoimmune NOD Mouse Diabetes
    Expression of Stress Proteins in Diabetes Mellitus: Detection of a Heat Shock Protein 60-like Protein in Pancreatic RINm5F -Cell Plasma Membranes
    Stress Proteins and Myocardial Protection
    Heat Shock Proteins in Eosinophilic Inflammation
    Heat Shock Proteins in Duchenne Muscular Dystrophy and Other Muscular Disease
    Mitochondrial Neuromuscular Disease Associated with Partial Deficiency of Heat Shock Protein 60

    Stress Proteins and Interactions with Proteins or Cells in Immunity

    Heat Shock Proteins as Chaperones of Unique and Shared Antigenic Epitopes of Human Cancers: A Novel Approach to Vaccination
    In Vivo Carrier Effect of Heat Shock Proteins in Conjugated Vaccine Constructs
    Major Histocompatibility Complex Class Ib Molecules: A Role in the Presentation of Heat Shock Proteins to the Immune System?
    Polyclonal Responses of T Cells to Heat Shock Proteins

    Biography

    Willem Van Eden (Edited by) , Douglas B. Young (Edited by)

    "
    …a comprehensive overview.
    …the editors have achieved a healthy balance between historical background, factual knowledge and informed conjecture.
    "-Annals of the Rheumatic Diseases

    "…an excellent resource.
    "-Trends in Endocrinology and Metabolism

    "…a valuable and necessary source of information for readers working in the various fields of medicine.
    "-Nahrung