Statistical Genomics: Linkage, Mapping, and QTL Analysis

Ben Hui Liu

December 29, 1997 by CRC Press
Reference - 648 Pages
ISBN 9780849331664 - CAT# 3166

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  • Covers background information, such as basic genetics, mating design, and genetic markers
  • Includes statistical theory for genomics and statistical principles and methods
  • Presents the theory and methods for searching genes controlling complex traits, known as Quantitative Trait Loci (QTL) mapping
  • Provides computer tools for genomic map construction and QTL analysis, as well as resampling techniques and information on computer simulation
  • Enhanced by useful statistical software, available on the Internet, that helps you implement many of the techniques presented in the book
  • Contains many different types of applications emphasizing the use of computers, and includes all of the latest statistical methods used today
  • Covers both the theory and the implementation of that theory, both of which are important in interpreting results
  • Details the recent concepts in statistical genomics, such as gene ordering, synteny detection and genetic map merging, mapping using natural populations, high resolution QTL mapping, and computer simulation
  • Summary

    Genomics, the mapping of the entire genetic complement of an organism, is the new frontier in biology. This handbook on the statistical issues of genomics covers current methods and the tried-and-true classical approaches.


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