Spike Timing: Mechanisms and Function

Patricia M. DiLorenzo, Jonathan D. Victor

May 2, 2013 by CRC Press
Reference - 442 Pages - 23 Color & 97 B/W Illustrations
ISBN 9781439838150 - CAT# K11729
Series: Frontiers in Neuroscience

USD$165.95

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Features

  • Brings together information about spike timing from a wide range of fields and perspectives
  • Presents theoretical and computational studies, as well as experimental studies in a variety of key model systems
  • Describes methods for measuring and analyzing spike timing
  • Provides a background for investigators to consider spike timing as it applies to their own work
  • Offers a view of the future direction of work related to mechanisms of spike timing, and its role in neural function
  • Presents a scientific basis for inclusion of impulse timing in the development of novel computational technologies

Summary

Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful and—until recently—perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. The heightened interest is due to several factors. These include the development of physiological tools for measuring the activity of neural ensembles and analytical tools for assessing and characterizing spike timing. These advances are coupled with a growing appreciation of spike timing’s theoretical importance for the design principles of the brain.

Spike Timing: Mechanisms and Function examines the function of spike timing in sensory, motor, and integrative processes, providing readers with a broad perspective on how spike timing is produced and used by the nervous system. It brings together the work and ideas of leaders in the field to address current thinking as well as future possibilities.

The first section of the book describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems.

Drawing together multiple perspectives, including theoretical and computational studies as well as experimental studies in a range of model systems, the book provides a firm background for investigators to consider spike timing as it applies to their own work. It also offers a glimpse of future advances related to mechanisms of spike timing and its role in neural function, such as the development of novel computational technologies.