Sites of Drug Action in the Human Brain uses the results of recent analyses of the regional brain distribution and binding pattern of drugs in the human brain. This new book specifically addresses drugs of abuse and treats the effects of various drugs on behavior and mood, as well as on metabolism and blood flow in the human brain. It also presents the methodological aspects of investigating the sites of drug action in the human brain.
Because it focuses on the living human brain, this book differs from other books on the subject, which primarily use the results of postmortem studies. Sites of Drug Action in the Human Brain therefore provides valuable information on the clinical aspects of drug intoxification, addiction, and toxicity.
Table of Contents
Localization and Characterization of Drug Binding Sites in the Human Brain: Methodological Considerations, A. Biegon and N.D. Volkow
Autoradiographic Localization of Benzodiazepine Receptors in the Human Brain Postmortem, J.M. Palacios, G. Mengod, and R. Cortes
In Vivo Imaging of Benzodiazepine Receptors with Positron Emission Tomography, K.A. Frey, R.A. Koeppe, and V.A. Holthoff
Effects of Benzodiazepines on Behavior, Mood, and Regional Cerebral Metabolism, J.T. Metz, H. de Wit, M. Cooper, and J. Metz
Quantitative Autoradiography of Cannabinoid Receptors in the Human Brain Postmortem, A. Biegon and I. Kerman
The Effects of Marihuana in the Human Brain Measured with Regional Brain Glucose Metabolism, N.D. Volkow, H. Gillespie, L. Tancredi, and L. Hollister
Quantitative Autoradiographic Localization and Characterization of Cocaine Binding Sites in the Human Brain Postmortem, A. Biegon, K. Dillon, N.D. Volkow, and J.S. Fowler
PET Studies of Cocaine in Human Brain, J.S. Fowler, N.D. Volkow, and A.P. Wolf
Radioautographic Distribution of Multiple Opioid, Sigma, and Phencyclidine Receptor Binding Sites in the Human Brain, R. Quirion, C. Pilapil, H. Allaoua, and I. Chaudieu
Imaging Opiate Receptors In Vivo, J.J. Frost
The Use of Positron Emission Tomography to Study the Acute Effects of Addictive Drugs on Cerebral Metabolism, M.J. Morgan and E.D. London
Discussion, M.J. Kuhar