Simulation for Designing Clinical Trials: A Pharmacokinetic-Pharmacodynamic Modeling Perspective

1st Edition

Hui Kimko, Stephen B. Duffull

CRC Press
Published December 12, 2002
Reference - 424 Pages
ISBN 9780824708627 - CAT# DK2039
Series: Drugs and the Pharmaceutical Sciences

For Instructors Request Inspection Copy

USD$180.00

Add to Wish List
FREE Standard Shipping!

Summary

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to clinical trial designs according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.

Instructors

We provide complimentary e-inspection copies of primary textbooks to instructors considering our books for course adoption.

Request an
e-inspection copy

Share this Title