Signaling Mechanisms Regulating T Cell Diversity and Function

Jonathan Soboloff, Dietmar J. Kappes

© 2017 - CRC Press
Published March 9, 2017
Reference - 258 Pages - 3 Color & 25 B/W Illustrations
ISBN 9781498705080 - CAT# K24749
Series: Methods in Signal Transduction Series

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  • Covers the great diversity in the way T cells are used in various immune responses
  • Focuses on the protective functions of T cells
  • Reviews the ways T-cells operate to minimize the emergence of autoimmunity
  • Includes contributions from an international team of leading researchers


T cells play a vital role mediating adaptive immunity, a specific acquired resistance to an infectious agent produced by the introduction of an antigen. There are a variety of T cell types with different functions. They are called T cells, because they are derived from the thymus gland. This volume discusses how T cells are regulated through the operation of signaling mechanisms. Topics covered include positive and negative selection, early events in T cell receptor engagement, and various T cell subsets.


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