This series reflects the tremendous impact of computational tools in the study and practice of biophysics and biochemistry today. The goal is to introduce the principles and methods for computer simulation and modeling of biologically important macromolecules. The titles cover both fundamental concepts and state-of-the-art approaches, with specific examples illustrating cutting-edge methodology. The series is designed to cover modeling approaches spanning multiple scales: atoms, molecules, cells, organs, organisms, and populations. Important methodological aspects of molecular modeling and simulations are presented together with real biological problems. In addition to educating students on basic principles and techniques, these books facilitate interdisciplinary research by bringing professionals up to speed on key advances in the field.
New books in the series are commissioned by invitation. Authors are also welcome to contact the Series Editor (Prof. Nikolay Dokholyan: [email protected]) or the publisher (Carolina Antunes, Physics Editor: [email protected]) to discuss new title ideas.
Modeling the 3D Conformation of Genomes
Coarse-Grained Modeling of Biomolecules
Max L. Berkowitz
June 18, 2019
Due to recent advancements in the development of numerical algorithms and computational hardware, computer simulations of biological membranes, often requiring use of substantial computational resources, are now reaching a mature stage. Since molecular processes in membranes occur on a multitude of...
Guido Tiana, Luca Giorgetti
January 23, 2019
This book provides a timely summary of physical modeling approaches applied to biological datasets that describe conformational properties of chromosomes in the cell nucleus. Chapters explain how to convert raw experimental data into 3D conformations, and how to use models to better understand...
April 16, 2018
The Latest Developments on the Role of Dynamics in Protein Functions Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods presents modern biomolecular computational techniques that address protein flexibility/dynamics at all levels of theory. An international...
Garegin A. Papoian
October 30, 2017
"The chapters in this book survey the progress in simulating biomolecular dynamics…. The images conjured up by this work are not yet universally loved, but are beginning to bring new insights into the study of biological structure and function. The future will decide whether this scientific...
August 21, 2014
Although molecular modeling has been around for a while, the groundbreaking advancement of massively parallel supercomputers and novel algorithms for parallelization is shaping this field into an exciting new area. Developments in molecular modeling from experimental and computational techniques...