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There is a growing body of evidence suggesting that the herpesvirus has a role in many vascular disorders. Each chapter in this book discusses in detail the role that herpesviruses play in the pathophysiological processes related to cholesterol metabolism and intracellular trafficking, cell proliferation, matrix production and arterial tissue remodelling, and thrombosis. The contributors highlight a wide range of cellular processes focused on the potential role that herpesviruses may play in the etiology and development of cardiovascular disease, from early childhood to adult stages of life.
Table of Contents
1. Developmental Hypothesis for Plaque Monoclonality 2. Animal Studies of Virus-Induced Atherosclerosis 3. Molecular Analysis of Herpesviruses in Atherogenesis 4. Transformation of Vascular Cells by Herpesviruses 5. Herpes Simplex Virus Infection of Vascular Cells and Its Effects on Extracellular Matrix 6. Etiological Link Between Cytomegalovirus and Restenosis/Atherosclerosis and Possible Molecular Mechanisms 7. Herpesviruses Effects on Pro-Inflammatory and Procoagulant Properties of Endothelial Cells 8. Cytomegalovirus - A Possible Initiation of Atherosclerosis - Role of Cytomegalovirus Infection in Vessel Wall Pathology 9. Herpesviral Induction of a Pro-Thrombotic and Pro-Atherosclerotic Phenotype in Arteries
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