Role of Cancer Stem Cells in Cancer Biology and Therapy

Thomas Dittmar, Kurt S. Zänker

March 1, 2013 by CRC Press
Reference - 332 Pages - 11 Color & 7 B/W Illustrations
ISBN 9781466577350 - CAT# K16784

USD$134.95

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Features

  • Summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology
  • Provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias
  • Reviews the role of CSCs in metastasis formation and initiation of cancer relapses
  • Examines the dark site of cancer therapy, including conventional cancer therapies that may lead to the origin of recurrence CSCs
  • Suppplies a brief overview of current concepts that may allow for a selective eradication of CSCs

Summary

This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark side of cancer therapy such as conventional cancer therapies that may lead to the origin of recurrence CSCs. Finally, it supplies a brief overview of current concepts that may allow for a selective eradication of CSCs.