Revival: Topology and Physics of Circular DNA (1992)

1st Edition

Alexander Vologodskii

CRC Press
December 31, 2018 Forthcoming
Reference - 192 Pages
ISBN 9781138562813 - CAT# K43547
Series: CRC Press Revivals

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Summary

Topology and Physics of Circular DNA presents comprehensive coverage of the physical properties of circular DNA. The author examines how topological constraints arising from cyclization of DNA lead to distinctive properties that make closed molecules radically different from linear DNA. The phenomenon of supercoiling, its geometric and topological analysis, and the formation of noncanonical structures in circular DNA under the influence of supercoiling are emphasized. The combination of consistent theoretical analysis and detailed treatment of major experimental approaches make Topology and Physics of Circular DNA an important reference volume for biophysicists, biochemists, molecular biologists, and researchers and students who want to expand their understanding of circular DNA.

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