Regulating with RNA in Bacteria and Archaea

1st Edition

Gisela Storz, Kai Papenfort

ASM Press
Published February 28, 2019
Reference - 400 Pages - 4 Color Illustrations
ISBN 9781683670230 - CAT# K406903

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USD$150.00

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Summary

For decades after the discoveries of messenger RNA, transfer RNA, and ribosomal RNA, it was largely assumed that the role of RNA in the cell was limited to shuttling the genomic message, chaperoning amino acids, and toiling in the ribosomes.

Eventually, hints that RNA molecules might have regulatory roles began to appear. With the advent of genomics and bioinformatics, it became evident that numerous other RNA forms exist and have specific functions, including small RNAs (sRNA), RNA thermometers, and riboswitches to regulate core metabolic pathways, bacterial pathogenesis, iron homeostasis, quorum sensing, and biofilm formation.

It is no longer a fair assumption that gene expression regulation is the provenance of proteins only or that control is exerted primarily at the level of transcription. This book makes clear that regulatory RNAs are key partners along with proteins in controlling the complex interactions and pathways found within prokaryotes.

 

Key selling features:

  • Microbial Genetics and Molecular Biology

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