Pharmaceutical Product Development: In Vitro-In Vivo Correlation

1st Edition

Chilukuri Dakshina Murthy, Gangadhar Sunkara, David Young

CRC Press
Published February 12, 2007
Reference - 224 Pages - 104 B/W Illustrations
ISBN 9780849338274 - CAT# DK827X
Series: Drugs and the Pharmaceutical Sciences

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Summary

During the last two decades, the pharmaceutical industry has been under pressure to reduce development costs and the time needed to bring drugs to market in order to maximize return on investment and bring treatments to patients sooner. To meet these ends, pharmaceutical scientists working in the differing areas of pharmacy, pharmaceutics, and pharmacokinetics are collaborating to address physicochemical and biological issues in the early stages of development to avoid problems in later stages. In Vitro-In Vivo Correlation (IVIVC) is a multidisciplinary tool that has been successfully applied in testing the effectiveness of a drug substance. The only comprehensive guide available on IVIVC, this source illustrates the emerging importance of IVIVC in the drug development process, and covers the most recent advances and regulatory perspectives on the role of IVIVC in the pharmaceutical industry.

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