1st Edition

Pharmaceutical Perspectives of Nucleic Acid-Based Therapy

Edited By Ram I. Mahato, Sung Wan Kim Copyright 2002
    560 Pages
    by CRC Press

    560 Pages
    by CRC Press

    Emphasizing its uses in cancer and cardiovascular and autoimmune diseases, Pharmaceutical Perspectives of Nucleic Acid-Based Therapy presents a comprehensive account of gene therapy, from development in the laboratory to clinical applications. Internationally acclaimed scientists discuss the potential use of lipids, peptides and polymers for the in vivo delivery of nucleic acids, the genesis of structure-synthesis-function interrelationships and the evolutionary approaches of these gene carriers. The book also addresses the influence of a viable gene expression system on disease by controlling gene regulation, transcription, translation and replication.

    Gene Expression. Modulation of Gene Expression. Biophysical Aspects of Nucleic Acids and Carriers. Intracellular Trafficking. Nucleic Acid Delivery Systems. Biodistribution and Pharmacokinetics. Clinical Applications of Gene Therapy.

    Biography

    Ram I. Mahato