Welcome to CRCPress.com! We have customized the Taylor & Francis India website to host CRC Press titles. Please choose www.TandFIndia.com to get the following benefits:
South Asia Editions of CRC Press titles with INR prices
Multiple options to purchase locally
All CRC Press products available
Your CRC Press login credentials will work on TandFIndia.com
Garland Science Website Announcement
The Garland Science website is no longer available to access and you have been automatically redirected to CRCPress.com.
All instructor resources (*see Exceptions) are now available on our Instructor Hub. Your GarlandScience.com instructor credentials will not grant access to the Hub, but existing and new users may request access here.
The student resources previously accessed via GarlandScience.com are no longer available to existing or new users.
This book provides a comprehensive review of the field of peptide biosynthesis. Individual chapters range from historical perspectives of the field to current knowledge regarding specific enzymes. Every step from gene to final bioactive peptide is covered in detail. Approximately two thirds of the book reviews the enzymes responsible for intracellular and extracellular peptide processing. Other chapters cover issues such as tissue-specific processing and the subcellular sorting of the peptides. New areas covered include the discovery, purification, characterization, and cDNA cloning of peptide processing enzymes involved with endopeptidase processing, carboxypeptidase processing, and C-terminal amidation; identification of the mammalian KEX-2 (subtilisin-like) family of proteases; identification of a second enzyme involved in C-terminal amidation; and the characterization of regulatory elements in neuropeptide genes and the associated DNA-binding proteins, such as CREB and related proteins, in addition to the Pit-1/GHF-1 family of proteins. The book's extensive coverage and 1000 references make it important reading material for new and established researchers in this rapidly expanding field.
Table of Contents
The Biosynthesis of Biologically Active Peptides: A Perspective (Donald F. Steiner). Themes in Neuropeptide Gene Regulation (Carolyn D. Minth and Jack E. Dixon). Signals for Intracellular Protein Sorting: Implications for Peptide Hormone Precursor Processing and Secretion (Dennis Shields). Tissue-Specific Peptide Processing (Ian Dickerson and Gilles Noël). Glycosylation, Phosphorylation, and Sulfation of Peptide Hormones and Their Precursors (Hugh P.J. Bennett). Peptide Processing Proteinases with Selectivity for Paired Basic Residues (Iris Lindberg and John C. Hutton). Peptide Processing at Monobasic Sites (Lakshmi Devi). Peptide Processing Exopeptidases: Amino- and Carboxypeptidases Involved with Peptide Biosynthesis (Lloyd D. Fricker). Modification of the N- and C-Termini of Bioactive Peptides: Amidation and Acetylation (Alan F. Bradbury and Derek G. Smyth). Extracellular Processing of Peptides (Chris J. Molineaux and Sherwin Wilk).
We provide complimentary e-inspection copies of primary textbooks to instructors considering our books for course adoption.
Most VitalSource eBooks are available in a reflowable EPUB format which allows you to resize text to suit you and enables other accessibility features. Where the content of the eBook requires a specific layout, or contains maths or other special characters, the eBook will be available in PDF (PBK) format, which cannot be reflowed. For both formats the functionality available will depend on how you access the ebook (via Bookshelf Online in your browser or via the Bookshelf app on your PC or mobile device).
CHOICE – Outstanding Academic Title – Award Winner
CHOICE – 2018 Outstanding Academic Title – Award Winner
Shingo Research and Professional Publication Award Winner
The country you have selected will result in the following:
Product pricing will be adjusted to match the corresponding currency.
The title will be removed from your cart because it is not available in this region.