Paracoccidioidomycosis continues to be a serious health problem among rural workers in many Latin American countries. This deep mycosis has many similarities to other deep mycoses that affect the developed world. Furthermore, P. brasiliensis is becoming an excellent tool for basic studies (e.g., dimorphism, hormone-mediated host interactions, ecology). Paracoccidioidomycosis is an important publication with 30 chapters covering every aspect of the disease from its etiological agent, P. brasiliensis, to the clinical manifestations and treatment. The chapters are written by 45 specialists, each one a leading figure in his or her area of research. This reference is the first of its kind to be written in English. The book is a valuable addition to the reference collections of basic researchers and applied mycologists, as well as clinicians and others working with infectious and tropical diseases. It can also be used for courses on medical mycology.
Table of Contents
1. Historical Evolution of the Knowledge on Paracoccidioidomycosis and Its Etiologic Agent, Paracoccidioides brasiliensis 2. Paracoccidioides brasiliensis: Morphology, Evolutionary Cycle, Maintenance During Saprophytic Life, Biology, Virulence, Taxonomy 3. Paracoccidioides brasiliensis: Ultrastructural Findings 4. Biochemistry of Paracoccidioides brasiliensis Dimorphism 5. Immunochemistry of Paracoccidioides brasiliensis Antigens 6. Experimental Paracoccidioidomycosis 7. Epidemiology and Paracoccidioidomycosis Infection 8. Ecology of Paracoccidioides brasiliensis 9. Pathology 10. Immunogenetics in Paracoccidioidomycosis 11. Cellular Immunity 12. Humoral Immunity 13.Pathogenesis 14. Interaction of Paracoccidioides brasiliensis with Host Defense Cells 15. General Clinical Aspects 16. Polar Forms of Paracoccidioidomycosis: The Disease in Childhood 17. The Gamut of Clinical Manifestations 18. Cutaneous Lesions 19. Oropharyngolaryngeal Lesions 20. Pulmonary Lesions: Clinical and Functional Aspects 21. Roentgenographic Patterns of Chest Lesions: The Use of Computerized Tomography in Paracoccidioidomycosis 22. Digestive Tract Lesions 23. Adrenocortical Involvement 24. Lymph Node Involvement 25. Neuroparacoccidioidomycosis 26. Bone and Joint Lesions 27. Mycologic Diagnosis