Ovarian Toxicology, Second Edition

Patricia B. Hoyer

September 30, 2017 by CRC Press
Reference - 387 Pages - 42 B/W Illustrations
ISBN 9781138199859 - CAT# K31517

USD$80.00

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Features

  • Presents a comprehensive review of environmental impacts on the ovary
  • Considers epidemiology and risk assessment
  • Provides an overview of normal ovarian function
  • Discusses current understanding of the causes and mechanisms of ovarian cancer
  • Discusses toxicology as it relates to ovarian cancer
  • Provides current information from regulatory agencies, such as the EPA, as well as academia

Summary

Today, we are exposed to an increasing number of chemicals in the environment and there is a growing awareness of the effects of these chemicals on the ovaries. Infertility resulting from environmental exposures may not be obvious until the reproductive life span is waning. As such, the potential for xenobiotic-induced infertility needs to be better understood.

In recent years, research into chemicals that have the potential to cause early menopause by destroying pre-antral ovarian follicles is gaining greater appreciation. Ovarian Toxicology, Second Edition represents a compilation of chapters prepared by researchers who have substantially contributed to our understanding of the impact of xenobiotics and environmental factors on ovarian function. The second edition substantially updates newly investigated ovotoxicants as well as improved mechanistic insights that have emerged since the first edition.

Topics include:

  • Ovarian physiology and the metabolism of xenobiotics
  • The effect of pesticides, heavy metals, phthalates, BPA, and cigarette smoking on the ovaries
  • Ovarian cancer, including endocrine effects and new perspectives on chemoresistance
  • Epidemiology and human health risk assessment for environmental chemicals and pharmaceuticals

The first book to focus specifically on ovarian toxicology, this resource is ideal for scientists in academia, regulatory agencies, and industry who would benefit from a survey of the impact of xenobiotic chemicals on ovarian function.

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