1st Edition
OMICS Applications in Biomedical, Agricultural, and Environmental Sciences
With the advent of new technologies and acquired knowledge, the number of fields in omics and their applications in diverse areas are rapidly increasing in the postgenomics era. Such emerging fields—including pharmacogenomics, toxicogenomics, regulomics, spliceomics, metagenomics, and environomics—present budding solutions to combat global challenges in biomedicine, agriculture, and the environment. OMICS: Applications in Biomedical, Agricultural, and Environmental Sciences provides valuable insights into the applications of modern omics technologies to real-world problems in the life sciences. Filling a gap in the literature, it offers a broad, multidisciplinary view of current and emerging applications of omics in a single volume.
Written by highly experienced active researchers, each chapter describes a particular area of omics and the associated technologies and applications. Topics covered include:
- Proteomics, epigenomics, and pharmacogenomics
- Toxicogenomics and the assessment of environmental pollutants
- Applications of plant metabolomics
- Nutrigenomics and its therapeutic applications
- Microalgal omics and omics approaches in biofuel production
- Next-generation sequencing and omics technology for transgenic plant analysis
- Omics approaches in crop improvement
- Engineering dark-operative chlorophyll synthesis
- Computational regulomics
- Omics techniques for the analysis of RNA splicing
- New fields, including metagenomics, glycomics, and miRNA
- Breast cancer biomarkers for early detection
- Environomics strategies for environmental sustainability
This timely book explores a wide range of omics application areas in the biomedical, agricultural, and environmental sciences. Throughout, it highlights working solutions as well as open problems and future challenges. Demonstrating the diversity of omics, it introduces readers to state-of-the-art developments and trends in omics-driven research.
The World of Omics and Applications in Biomedical Sciences
Proteomics: Techniques, Applications, and Challenges
Namasivayam Elangovan
Epigenome: Genomic Response to Environmental Eccentricities
Anjana Munshi, Srirama Krupanidhi, and Yog Raj Ahuja
Epigenomics: Basics and Applications
Jaspreet Kaur and Jyotdeep Kaur
Pharmacogenomics for Individualized Therapy
Eugenia Ch. Yiannakopoulou
Pharmacogenomic Knowledge to Support Personalized Medicine: The Current State
Casey Lynnette Overby and Houda Hachad
Toxicogenomics: Techniques, Applications, and Challenges
Indra Arulselvi Padikasan and Nancy Daliel
The World of Noncoding RNAs
Winnie Thomas, Qurratulain Hasan, Konagurtu Vaidyanath, and Yog Raj Ahuja
Spliceomics: The OMICS of RNA Splicing
Atmakuri Ramakrishna Rao, Tanmaya Kumar Sahu, and Nishtha Singh
Computational Regulomics: Information Theoretic Approaches toward Regulatory Network Inference
Vijender Chaitankar, Debmalya Barh, Vasco Azevedo, and Preetam Ghosh
Glycomics: Techniques, Applications, and Challenges
Veeraperumal Suresh, Chinnathambi Anbazhagan, and Dakshanamurthy Balasubramanyam
Breast Cancer Biomarkers
Rajneesh K. Gaur
Use of Protein Biomarkers for the Early Detection of Breast Cancer
Birendra Kumar, Purnmasi Ram Yadav, and Surender Singh
The World of Omics and Applications in Plant and Agricultural Sciences
Genomics, Proteomics and Metabolomics: Tools for Crop Improvement under Changing Climatic Scenarios
Hifzur Rahman, D.V.N. Sudheer Pamidimarri, Ramanathan Valarmathi, and Raveendran Muthurajan
Application of Next-Generation Sequencing for Abiotic Stress Tolerance
Tapan Kumar Mondal and Keita Sutoh
Next-Generation Sequencing and Assembly of Bacterial Genomes
Artur Silva, Rommel Ramos, Adriana Carneiro, Sintia Almeida, Vinicius De Abreu, Anderson Santos, Siomar Soares, Anne Pinto, Luis Guimarães, Eudes Barbosa, Paula Schneider, Vasudeo Zambare, Debmalya Barh, Anderson Miyoshi, and Vasco Azevedo
Towards Engineering Dark-Operative Chlorophyll Synthesis Pathways in Transgenic Plastids
Muhammad Sarwar Khan
Utilization of Omics Technology to Analyze Transgenic Plants
Marisela Rivera-Domínguez and Martín-Ernesto Tiznado-Hernández
Microalgal Omics and Their Applications
Shanmugam Hemaiswarya, Rathinam Raja, Ramanujam Ravikumar, Annamalai Yogesh Kumar, and Isabel S. Carvalho
Plant Metabolomics: Techniques, Applications, Trends, and Challenges
Shoaib Ahmad
Nutraceuticals: Applications in Biomedicine
Vellingiri Vadivel
Genomic Resources of Agriculturally Important Animals, Insects, and Pests
Sarika, Anu Sharma, Anil Rai, Mir Asif Iquebal, and Poonam Chilana
The World of Omics and Applications in Environmental Sciences
Applications of Molecular Spectroscopy in Environmental and Agricultural Omics
Daniel Cozzolino
Metagenomics: Techniques, Applications, and Challenges
Jyoti Vakhlu and Puja Gupta
Toxicogenomics in the Assessment of Environmental Pollutants
Luciana B. Crotti and Luis A. Espinoza
Omics Approaches in Biofuel Production for a Green Environment
Atul Grover, Patade Vikas Yadav, Maya Kumari, Sanjay Mohan Gupta, Mohommad Arif, and Zakwan Ahmed
Environomics: Omics for the Environment
Dinesh K. Yadav, Neelam Yadav, and Satyendra Mohan Paul Khurana
Index
Biography
Debmalya Barh is the founder and president of the Institute of Integrative Omics and Applied Biotechnology (IIOAB), India, a global platform for multidisciplinary research and advocacy. He is a consultant biotechnologist and has more than 12 years of rich experience in interdisciplinary omics fields. His research areas include integrative omics–based translational researches, target and targeted drug discovery, biomarkers, pharmacogenomics, neutrigenomics, cancer, neuroscience, cardiovascular diseases, infectious and metabolic diseases, and plant, animal, and environmental biotechnology. As an active scientist in the field, he works with nearly 200 researchers from more than 80 institutes across 25 countries. He has edited a number of research reference books in the areas of omics, biomarkers, and other advanced domains in biology. He also serves as an editorial and review board member for several professional international research journals of global repute.
Vasudeo Zambare is a biochemist. He previously worked at Agharkar Research Institute, India, and the Center for Bioprocessing Research and Development at the South Dakota School of Mines and Technology, USA. His current research concentrates on the use of omics technologies in agriculture, functional food, and environmental sciences. He has published more than 150 peer-reviewed articles and is editor-in-chief, technical editor, associate editor, editorial board member, or advisory member of more than 80 international research journals. He is a fellow member of several international societies, including the Institute of Integrative Omics and Applied Biotechnology (IIOAB).
Vasco Azevedo is a full professor in molecular biology and genetics at the Federal University of Minas Gerais, Brazil. He is a pioneer scientist in lactic acid bacteria and Corynebacterium pseudotuberculosis and a well-known scientist in bacterial genomics, transcriptomics, proteomics, and metabolomics. His research also involves omics approaches in livestock and agricultural biotechnology in the development of new omics-based vaccines and diagnostics against infectious diseases. He has published 160 research articles and 15 book chapters. He is an associate editor of several journals, including Genetics and Molecular Research, Microbial Cell Factories, and The IIOAB Journal, and an editorial board member of a number of international journals.