We have come to realize that optimal nutrient intake is determined by very specific genetic messages. This realization has led to an entirely new approach to understanding nutrition – the exploration of nutrient effects on gene expression.
Edited by leading experts in the field, Nutrient–Gene Interactions in Health and Disease provides an update of this important and rapidly growing field of research, presenting examples of both macronutrients and micronutrients as they affect gene expression. It addresses lipogenesis, fatty acid oxidation, fatty acid desaturation, and glucose transporters. It also discusses genes that associate with obesity or cancer, genes that are affected by vitamins A and D, and several other topics.
Genetic regulation of nutritional response is at the heart of our understanding of nutrition science. Nutrient–Gene Interactions in Health and Disease presents the latest information about how specific processes in intermediary metabolism are genetically regulated, giving you a new understanding of such diseases as obesity, diabetes, alcoholism, anemia, and other diseases with both a nutrient and a genetic component.
Table of Contents
Dietary and Hormonal Regulation of the Mammalian Fatty Acid Synthase Gene, Kristin Morris, Yanxin Wang, Suyeon Kim, and Naima Moustaïd-Moussa
Nutrition and Adipocyte Gene Expression, Ron F. Morrison and Stephen R. Farmer
Regulation of the Stearoyl-CoA Desaturase Genes by Dietary Fat: Role of Polyunsaturated Fatty Acids, James M. Ntambi and Young-Cheul Kim
Fatty Acids, White Adipose Tissue Development and Adipocyte Differentiation, Gérard Ailhaud
Acyl-CoA Synthetase 1: Regulation and Role in Metabolism, Pamela J. Smith
Nutritional Regulation of Fatty Acid Transport Protein Expression, Judith Storch and Fiona M. Herr
Alcohol and Gene Expression in the Central Nervous System, Matthew T. Reilly, Christoph Fehr, and Kari J. Buck
Nutrient Control of Insulin-Stimulated Glucose Transport in 3T3-L1 Adipocytes, Joseph P. Hwang, Greg Marshall, Daniel Fallon, and Susan C. Frost
Prohormone Processing and Disorders of Energy Homeostasis, Jung Han Kim and Jürgen K. Naggert
The Agouti Gene in Obesity: Central and Peripheral Mechanisms, and Therapeutic Implications, Michael B. Zemel, Ph.D., Bingzhong Xue, B. Med, and Hang Shi, B. Med
Dietary Fats and APC-Driven Intestinal Tumorigenesis, Jay Whelan and Michael F. McEntee
Body Weight Regulation, Uncoupling Proteins, and Energy Metabolism, Sheila Collins, Wenhong Cao, Tonya M. Dixon, Kiefer W. Daniel, Hiroki Onuma, and Alexander V. Medvedev
Vitamin A and Gene Expression, Peter McCaffery, Fausto Andreola, Valeria Giandomenico, and Luigi M. De Luca
Vitamin A and Mitochondrial Gene Expression, Helen B. Everts and Carolyn D. Berdanier
Vitamin D and Gene Expression, Anthony W. Norman and Elaine D. Collins
Vitamin E and Gene Expression, Simin Nikbin Meydani, Kate J. Claycombe, and Catarina Sacristán
Differential Regulation and Function of Glutathione Peroxidases and other Selenoproteins, Xin Gen Lei
Ferritin: A Novel Human Ferritin Heavy-Chain MRNA is Predominantly Expressed in the Adult Brain, Madhu S. Dhar
“…a good resource for researchers in the area of biochemistry, nutritional sciences, cell biology, genetics and physiology, especially those interested in lipid metabolism.”
— Journal of Nutrition Education and Behavior