Nonlinear Models for Repeated Measurement Data

1st Edition

Marie Davidian, David .M. Giltinan

Chapman and Hall/CRC
Published June 1, 1995
Reference - 360 Pages
ISBN 9780412983412 - CAT# C8341
Series: Chapman & Hall/CRC Monographs on Statistics and Applied Probability

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Summary

Nonlinear measurement data arise in a wide variety of biological and biomedical applications, such as longitudinal clinical trials, studies of drug kinetics and growth, and the analysis of assay and laboratory data. Nonlinear Models for Repeated Measurement Data provides the first unified development of methods and models for data of this type, with a detailed treatment of inference for the nonlinear mixed effects and its extensions. A particular strength of the book is the inclusion of several detailed case studies from the areas of population pharmacokinetics and pharmacodynamics, immunoassay and bioassay development and the analysis of growth curves.