Nicotine research has been conducted for the better part of a century, but with the discovery of the relationship of nicotinic systems to Alzheimer's disease, the differentiation of nicotinic receptor subtypes, and the development of novel nicotinic ligands, the field of nicotine research has exploded. This book will provide you reference to the latest research methods and findings concerning nicotinic neural systems.
Featuring a unique approach, Nicotinic Receptors in the Nervous System provides integrated coverage of cutting-edge research concerning neuronal nicotinic systems relevant to smoking addiction and cognitive dysfunction. By bringing together molecular and neurochemical applications, this book provides the key to understanding function and dysfunction of nicotinic systems and how they are significant for disease, addiction, and the development of novel drug treatments.
Within the next several years, it is very promising that clinical research will support the use of nicotinic treatments for addiction, pain, and cognitive and motor dysfunction. Nicotinic Receptors in the Nervous System provides you with the basic mechanistic background for these treatments as well as the functional assessment necessary to determine therapeutic effects.
Table of Contents
Some Methods for Studies of Nicotinic Acetylcholine Receptor Pharmacology, R.J. Lukas, J.D. Fryer, J.B. Eaton, and C.L. Gentry
Presynaptic Nicotinic Acetylcholine Receptors: Subtypes Mediating Neurotransmitter Release, S. Wonnacott, A. Mogg, A. Bradley, and I.W. Jones
Nicotinic Receptors in the Periphery
Effects of Nicotine on Dopaminergic Neurotransmission, P.P. Rowell
Nicotinic Receptors in the Periphery, S. Jones, H. Lo, and S.A. Simom
Nicotinic Cholinergic Receptors as Targets in Pain Control, M.I. Damaj and C.M. Flores
Mouse Models to Evaluate Genetic Influences on Responses to Nicotine, M.J. Marks and A.C. Collins
Nicotinic Involvement in Cognitive Function in Rats, E.D. Levin and A.H. Rezvani
Nicotine and Cognition in Young and Aged Nonhuman Primates, J.J. Buccafusco and A.V. Terry, Jr.
Evaluation of Pharmacologic Treatments for Smoking Cessation, J.E. Rose
Nicotine and Schizophrenia, J.P. McEvoy
Nicotinic Medications and Tourette's Disorder, R.D. Shytle, A.A. Silver, M. Newman, B.J. Wilkinson, and P.R. Sandberg
Nicotine Effects on Attention Deficit Hyperactivity Disorder, E.D. Levin
Clinical Methodologies in the Examination of Nicotinic Effects, A. Potter and P.A. Newhouse
Nicotinic Systems: An Integrated Approach, E.D. Levin
"Well known researchers from the Old and New Worlds contributed to this book…presents an integrated approach to nicotine research that should help to identify critical neuropharmacological mechanisms for both adverse and potentially therapeutic effects of nicotine. Edward Levine has contributed much to the development of nicotine research on cognitive functions."
Jacques le Houezec, SRNT Newsletter, October/November 2002