Attracting the attention of the medical community, exhaled breath condensate is a completely non-invasive method for sampling secretions from the airways. Analysis of exhaled breath condensate is potentially useful for monitoring airway inflammation and in pharmacological therapy. With its non-invasive nature, this method may be suitable for longitudinal studies even in children and in patients with lung severe disease.
New Perspectives in Monitoring Lung Inflammation provides an introduction to the analysis of exhaled breath condensate for monitoring lung inflammation. The book presents current knowledge on the physicochemical properties of exhaled breath condensate and its formation in the airways and covers important aspects of the methodology. It details markers, and classes of markers, of airway inflammation in separate chapters and discusses the use of the technique in adults and children. The text also reviews the implications for drug development and future research. The volume concludes with an overview of lung inflammation focusing on basic and clinical pharmacology of important mediators.
Presenting a comprehensive view of exhaled breath condensate, the text explains how this method could play a major role in the diagnosis and therapy of lung diseases, and may launch a new era in respiratory medicine.
Table of Contents
Exhaled Breath Condensate: A New Approach to Monitoring Lung Inflammation, Peter J. Barnes
Analysis of Exhaled Breath Condensate: Methodological Issues, Paolo Montuschi
Exhaled Breath Condensate: Formation and Physicochemical Properties, Richard M. Effros
Isoprostanes, Prostanoids, and Leukotrienes in Exhaled Breath Condensate, Paolo Montuschi
Hydrogen Peroxide in Exhaled Breath Condensate, Wendy J.C. van Beurden and Richard Dekhuijzen
Measurement of Exhaled Breath Condensate pH: Implications for Pathophysiology and Monitoring of Inflammatory Airway Diseases, Benjamin Gaston and John F Hunt
Nitric Oxide-Derived Products in Exhaled Breath Condensate, Sergei A. Kharitonov
Analysis of Exhaled Breath Condensate in Children, Rijn Jobsis and Philippe P.R. Rosias
Exhaled Breath Condensate: Comparisons with Other Methods for Assessing Lund Inflammation, Philip Silkoff and Christopher A. Bates
Analysis of Exhaled Breath Condensate: Potential Implications for Diagnosis and Therapy of Lung Diseases, Umur Hatipoglu and Israel Rubinstein
Analysis of Exhaled Breath Condensate: Directions for Future Research, Jon L. Freels and Richard A. Robbins
The Role of Leukotrienes and Prostonoids in Airway Inflammation, James R. Sheller, R. Stokes Peebles, and Ryszard Dworski
Neurogenic Inflammation in the Airways, Guy Joos, Katelijne O. de Swert, and Romain A. Pauwels
The Role of Cytokines and Chemokines in Airway Inflammation, Louise Donnelly and Suzanne Traves
"…an excellent introduction of the analysis of exhaled breath condensate."