Neural Plasticity and Memory: From Genes to Brain Imaging

Federico Bermudez-Rattoni

April 17, 2007 by CRC Press
Reference - 368 Pages - 8 Color & 49 B/W Illustrations
ISBN 9780849390708 - CAT# 9070
Series: Frontiers in Neuroscience


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  • Explores the molecular mechanisms of brain plasticity, examining the impact of information storage and retrieval
  • Examines the synaptic communication elements identified as being susceptible to modification through experience
  • Discusses recent work in memory research including those involving brain imaging
  • Emphasizes the methodological and conceptual problems inherent at different levels of analysis
  • Provides an interdisciplinary review of research conducted on the neurobiology of memory
  • Summary

    A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies.

    The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function.

    Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.