Providing an up-to-date overview of the field, this reference presents extensive discussions on a wide range of approaches for molecular imprinting written by pioneering experts on the subject. Molecularly Imprinted Materials: Science and Technology offers experimental protocols that exemplify specific techniques, as well as detailed surveys on molecular imprinting research and applications.
Provides a comprehensive tutorial for those who wish to learn basic techniques and make new contributions to the field, as well as in-depth discussions, guidelines, and experimental protocols to help beginners gain a jump-start in the field of molecular imprinting
The book examines the recent evolution of the technology, offering step-by-step instruction on methods to design and optimize molecularly imprinted polymers and suggestions, recommendations, and troubleshooting strategies for alternative approaches and improvements discussed in the text.
about the editors...
MINGDI YAN is Associate Professor, Department of Chemistry, Portland State University, Oregon. After serving as a senior research scientist at Ikonos Corporation, Portland, Oregon, she joined the Portland State University faculty and now leads a research group in organic and polymeric materials science. She received the B.S. degree in polymer physics from the University of Science and Technology, China, and the Ph.D. degree in organic chemistry from the University of Oregon.
OLOF RAMSTRÖM is Associate Professor, Royal Institute of Technology, Stockholm, Sweden. After serving with Professor Jean-Marie Lehn at Université Louis Pasteur, Strasbourg, France, he joined the Royal Institute of Technology and is now leading a group specializing in supramolecular chemistry and molecular recognition. He received the M.Sc. degree in chemical engineering and the Ph.D. degree in bioorganic chemistry/applied biochemistry from Lund Institute of Technology/Lund University, Sweden.
Table of Contents
Molecular Imprinting - An Introduction
A Brief History of the "New Era" of Molecular Imprinting
The Non-Covalent Approach
The covalent and Other Stoichiometric Approaches
The Semi-Covalent Approach
The Use of Metal Coordination for Controlling the Microenvironment of Imprinted Polymers
Synthesis and Selection of Functional and Structural Monomers
Combinatorial Approaches to Molecular Imprinting
Imprinting in Inorganic Matrices
Post Modification of Imprinted Polymers
Molecular Imprinting Using Hybrid Materials as Host Matrices
Thermodynamic Considerations and the Use of Molecular Modeling as a Tool for Predicting MIP Performances
Selectivity in Molecularly Imprinted Matrices Binding Isotherms
Molecularly Imprinted Polymer Beads
Molecularly Imprinted Polymer Films and Membranes
Micromonoliths and Microfabricated Molecularly Imprinted Polymers
Metal Ion selective Molecularly Imprinted Materials
Solid Phase Extraction and Byproduct Removal
Applications of Molecularly Imprinted Materials as Enzyme Mimics
Application of MIPs as Antibody Mimics in Immunoassays
Molecularly Imprinted Polymers as Recognition Elements in Sensors: Mass and Electrochemical Sensors
Molecularly Imprinted Polymers as Recognition Elements in Optical Sensors
"The editors have done an excellent job in soliciting chapters on specific topics and organizing them thematically to provide a volume in which the chapters compliment each other."