Molecular Biology of Assemblies and Machines

Alasdair Steven, Wolfgang Baumeister, Louise N. Johnson, Richard N. Perham

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March 15, 2016 by Garland Science
ISBN 9781134982820 - CAT# YE82740

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• Uses vivid illustrations to convey the ways in which macromolecular structures assemble and how they interact with other complexes and organelles in the cell.
• Written as the go-to reference for advanced students and researchers in biochemistry, molecular biology, biophysics, cell biology, chemistry, structural biology, immunology, microbiology, and medicine.
• Features a searchable glossary online, as well as flashcards, for testing student vocabulary.
• Chapters contain boxes exploring difficult concepts in more depth and end with a curated list of references for further reading.
• Two appendices provide a “Field Guide” to commonly encountered protein folds and descriptions of the main methods currently used in the practice of structural biology.


Molecular Biology of Assemblies and Machines presents a comprehensive narrative describing the structures of macromolecular complexes and how they assemble and interact. Richly illustrated, it is written for advanced undergraduates, graduate students, and researchers in biochemistry, structural biology, molecular biology, biophysics, cell biology, and microbiology, and will also appeal to those in chemistry, immunology, and medicine.

Essentially all major biological activities are performed by assemblies of macromolecules (proteins, RNA, and DNA) acting in concert. These assemblies are dynamic and many are endowed with machine-like properties. This unique book explores the molecular mechanisms employed at the critical level between individual macromolecules and cells and organelles.

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