This new edition brings you up-to-date on the role of pharmaceutics and its future paradigms in the design of medicines. Contributions from over 30 international thought leaders cover the core disciplines of pharmaceutics and the impact of biotechnology, gene therapy, and cell therapy on current findings. Modern Pharmaceutics helps you stay current with the basic sciences, systems, applications, and advances in drug development—from materials used in formulations and dosage form design and manufacture, to testing in clinical trials.
Improve research and development strategies with brand new content on:
• methods of in vivo imaging of dosage forms
• excipients, tablets, and aerosols—from physical chemistry to dosage form
• solid state drug delivery
• biotechnology-based pharmaceuticals
• modern evaluation techniques for medicinal products
• pharmaceutical nanotechnology
• pharmaceutical physics
• pediatric and geriatric medication
• routes of administration
• paradigms in pharmaceutical research
Volume 1:
1. Pharmaceutics: New Challenges, New Paradigms
Alexander T. Florence and Juergen Siepmann
2. Principles of Drug Absorption
Michael Mayersohn
3. Pharmacokinetics
David W. A. Bourne
4. Factors Influencing Oral Drug Absorption and Drug Availability
Juergen Siepmann, Florence Siepmann, and Alexander T. Florence
5. Effect of Route of Administration and Distribution on Drug Action
Maureen D. Donovan
6. In Vivo Imaging of Dosage Forms
Zheng-Rong Lu
7. Chemical Kinetics and Drug Stability
David Attwood and Rolland I. Poust
8. The Solid State
Alastair J. Florence
9. Excipient Design and Characterization
Graham Buckton
10. Preformulation
Gavin W. Halbert
11. Disperse Systems
Wandee Rungseevijitprapa, Florence Siepmann, Juergen Siepmann, and Ornlaksana Paeratakul
12. Surfactants
David Attwood
13. Tablet Dosage Forms
Murat Turkoglu and Adel Sakr
14. Hard- and Soft-Shell Capsules
Larry L. Augsburger
15. Parenteral Products
James C. Boylan and Steven L. Nail
Index
Volume 2:
1. Time-Controlled Drug Delivery Systems
Juergen Siepmann and Florence Siepmann
2. Bioequivalence
Panos Macheras, Christos Reppas, and Mira Symillides
3. Cutaneous and Transdermal Delivery—Processes and Systems of Delivery
Guang Wei Lu and Gordon L. Flynn
4. Design and Evaluation of Ophthalmic Pharmaceutical Products
Paul J. Missel, John C. Lang, Denise P. Rodeheaver, Rajni Jani, Masood A. Chowhan, James Chastain, and Terry Dagnon
5. Delivery of Drugs by the Pulmonary Route
Anthony J. Hickey and Heidi M. Mansour
6. Pediatric and Geriatric Pharmaceutics and Formulation
Jörg Breitkreutz and Catherine Tuleu
7. Biotechnology-Based Pharmaceuticals
Lene Jorgensen, Hanne Moerck Nielsen, and Sven Frokjaer
8. Veterinary Pharmaceutical Dosage Forms
Michael J. Rathbone and Todd P. Foster
9. Target-Oriented Drug Delivery Systems
Vijay Kumar
10. New Imaging Methods for Dosage Form Characterization
Colin D. Melia, Barry Crean, Samuel R. Pygall, and Hywel D. Williams
11. Aspects of Pharmaceutical Physics
Göran Frenning and Göran Alderborn
12. Pharmaceutical Aspects of Nanotechnology
Alexander T. Florence
13. Dosage Forms for Personalized Medicine: From the Simple to the Complex
Alexander T. Florence and Juergen Siepmann
Index
Biography
Alexander T. Florence, Juergen Siepmann