Metal Ions in Biological Systems: Volume 32: Interactions of Metal Ions with Nucleotides: Nucleic Acids, and Their Constituents

1st Edition

Astrid Sigel, Helmut Sigel

CRC Press
Published February 5, 1996
Reference - 854 Pages
ISBN 9780824795498 - CAT# DK5252
Series: Metal Ions in Biological Systems

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Volume 32 covers metal ion bonding to phosphate, sugar and nucleobase residues; the ambidentate as well as the stacking properties of nucleotides; kinetic aspects as well as properties of nucleobase and nucleotide analogs; and the oligonucleotides and nucleic acids. It examines electron transfer reactions over a large number of base repairs in DNA, the role of metal ions in ribozymes, ternary metal-nucleic acid base-protein complexes, metal responsive gene regulation, and the structure-activity relationships of anticancer drugs and their action on DNA, including cisplatin and the role of proteins.


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