This volume is devoted to the research area regarding the biological properties of metal alkyl derivatives, offering an authoritative account of this subject by 16 scientists. In 11 chapters, Biological Properties of Metal Alkyl Derivatives highlights, in detail, derivatives of germanium, tin, lead, arsenic, antimony, selenium, tellurium, cobalt (vitamin B12 derivatives) and nickel (coenzyme F430), including the role of (mainly) micro-organisms in their formation. The derivatives of indium, thallium, bismuth, various transition metals and mercury are also covered to some extent, as are those of the non-metals silicon, phosphorus and sulfur, and the haloperoxidase route of the biogenesis of halomethanes by fungi and plants. The properties of these alkyl derivatives, their biosynthesis, including mechanistic aspects, their appearance in waters (rivers, lakes, oceans) and sediments, and their physiological and toxic effects are summarized.
Table of Contents
Global bioalkylation of the heavy elements, John S. Thayer; analysis of organometallic compounds in the environment, Darren Mennie and Peter J. Craig; biogeochemistry of methylgermanium species in natural waters, Brent L. Lewis and H. Peter Mayer; biological properties of alkyltin compounds, Yasuaki Arakawa and Osamu Wada; biological properties of alkyl derivatives of lead, Yukio Yamamura and Fumio Arai; metabolism of alkyl arsenic and antimony compounds, Marie Vahter and Erminio Marafante; biological alkylation of selenium and tellurium, Ulrich Karlson and William T. Frankenberger Jr; making and breaking the co-alkyl bond in B12 derivatives, John M. Pratt; methane formation by methanogenic bacteria - redox chemistry of coenzyme F430, Bernhard Jaun; synthesis and degradation of organomercurials by bacteria, Helmut Sigel and Astrid Sigel; biogenesis and role of halomethanes in fungi and plants, David B. Harper.