Norma K Dunlap, Donna M Huryn
Published April 17, 2018
Textbook - 496 Pages - 588 Color Illustrations
ISBN 9780815345565 - CAT# Y214689
For Instructors Request Inspection Copy
SAVE ~$17.25 on each
Medicinal Chemistry teaches essential concepts by focusing on how the field is actually practiced, melding real-world research experience with basic principles and modern methods. Written by practicing medicinal chemists, this textbook is intended for advanced undergraduates and first-year graduate students in biology, chemistry, and biochemistry. Pre-medical or pre-pharmacy students and professionals entering the drug discovery field will also find it a useful reference. Building on a foundation of synthetic organic chemistry and structural biology, the book interweaves therapeutics, case studies, historical context, and techniques for discovering, developing, and optimizing new drugs. Chapters are richly illustrated and include problems and annotated journal references with accompanying exercises and answers.
PART I: Drug Discovery and Development
1. Historical Perspective and Overview of Drug Discovery
2. Drug discovery: Hit and Lead Discovery
3. Drug Discovery: Optimization of Lead Properties
PART II: Classes of Drug Targets
4. Medicinal Chemistry Strategies Used in Lead Optimization
5. The Process of Developing a Drug from an Optimized Lead
6. Receptors as Drug Targets
7. Enzymes as Drug Targets
8. Protein-Protein Interactions and Lipids as Drug Targets
9. DNA and RNA as Drug Targets
PART III: Selected Therapeutic Areas
10. Anti-Cancer Drugs
11. Infectious Diseases I: Antiviral and Antifungal Drugs
12. Infectious Diseases II: Antibacterial and Antiparasitic Drugs
13. Drugs Acting on the CNS
|May 21, 2018||Instructor Downloads||Instructor Resources
To gain access to the instructor resources for this title, please visit the Instructor Resources Download Hub.
You will be prompted to fill out a registration form which will be verified by one of our sales reps.
We provide complimentary e-inspection copies of primary textbooks to instructors considering our books for course adoption.